PCDH12 Antikörper (N-Term)

Produktnummer ABIN1888050

Produktdetails anti-PCDH12 Antikörper

Target: PCDH12 (Protocadherin 12 (PCDH12))

Bindungsspezifität: N-Term

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PCDH12 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Kreuzreaktivität (Details): This antibody is predicted to not cross-react with PCDH18.

Aufreinigung: Affinity chromatography purified via peptide column

Immunogen: 17 amino acid peptide near the amino terminus of human PCDH12.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Handhabung: Avoid freezing and thawing repeatly.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 4 °C for short term use.Store at -20 °C for long term preservation.

Details zu PCDH12

Target: PCDH12 (Protocadherin 12 (PCDH12))

Andere Bezeichnung: PCDH12 (PCDH12 Produkte)

Synonyme: PCDH12 antikoerper, VE-cadherin-2 antikoerper, VECAD2 antikoerper, Pcdh14 antikoerper, VE-cad-2 antikoerper, protocadherin 12 antikoerper, PCDH12 antikoerper, Pcdh12 antikoerper

Hintergrund: Protocadherins comprise the largest group within the cadherin family of calcium-dependent cell-cell adhesion molecules.Protocadherin 12 (PCDH12) was initially identified through PCR screening of mouse heart microvascular endothelial cell RNA, further experiments revealed its mRNA to be strongly expressed in highly vascularized organs such as lung and kidney, in addition to glycogen-rich trophoblasts in the placenta.PCDH12-null mice are viable and fertile, but show reduced placental and embryonic sizes when compared to wild-type mice.Further studies showed significant expression changes in 2, 289 genes, including those involved in tissue morphogenesis, angiogenesis, cell-matrix adhesion and migration, immune response and chromatin remodeling.
Synonyms: Protocadherin 12, vascular endothelial cadherin 2, VE-cadherin 2, VECAD2

NCBI Accession: NP_057664

Pathways: Cellular Glucan Metabolic Process