PCDH12 Antikörper (Middle Region)

Produktnummer ABIN2782896

Produktdetails anti-PCDH12 Antikörper

Target: PCDH12 (Protocadherin 12 (PCDH12))

Bindungsspezifität: Middle Region

Reaktivität: Human, Ratte, Rind (Kuh), Meerschweinchen, Pferd, Hund, Schwein

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PCDH12 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: SSRPFLLTTI VARDADSGAN GEPLYSIRSG NEAHLFILNP HTGQLFVNVT

Homologie: Cow: 85%, Dog: 92%, Guinea Pig: 85%, Horse: 86%, Human: 100%, Pig: 92%, Rat: 86%

Produktmerkmale: This is a rabbit polyclonal antibody against PCDH12. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human PCDH12

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 1184 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu PCDH12

Target: PCDH12 (Protocadherin 12 (PCDH12))

Andere Bezeichnung: PCDH12 (PCDH12 Produkte)

Synonyme: PCDH12 antikoerper, VE-cadherin-2 antikoerper, VECAD2 antikoerper, Pcdh14 antikoerper, VE-cad-2 antikoerper, protocadherin 12 antikoerper, PCDH12 antikoerper, Pcdh12 antikoerper

Hintergrund: PCDH12 belongs to the protocadherin protein family, a subfamily of the cadherin superfamily. It consists of an extracellular domain containing 6 cadherin repeats, a transmembrane domain and a cytoplasmic tail that differs from those of the classical cadherins. The function of this cellular adhesion protein is undetermined but mouse protocadherin 12 does not bind catenins and appears to have no affect on cell migration or growth.This gene belongs to the protocadherin gene family, a subfamily of the cadherin superfamily. The encoded protein consists of an extracellular domain containing 6 cadherin repeats, a transmembrane domain and a cytoplasmic tail that differs from those of the classical cadherins. The gene localizes to the region on chromosome 5 where the protocadherin gene clusters reside. The exon organization of this transcript is similar to that of the gene cluster transcripts, notably the first large exon, but no significant sequence homology exists. The function of this cellular adhesion protein is undetermined but mouse protocadherin 12 does not bind catenins and appears to have no affect on cell migration or growth.
Alias Symbols: VE-cadherin-2, VECAD2
Protein Size: 1184

Molekulargewicht: 126 kDa

Gen-ID: 51294

NCBI Accession: NM_016580, NP_057664

UniProt: Q9NPG4

Pathways: Cellular Glucan Metabolic Process