PTK7 Antikörper (N-Term)

Produktnummer ABIN1887910

Produktdetails anti-PTK7 Antikörper

Target: PTK7 (PTK7 Protein tyrosine Kinase 7 (PTK7))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PTK7 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Aufreinigung: Affinity chromatography purified via peptide column

Immunogen: 15 amino acid peptide from near the amino terminus of human PTK7.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Handhabung: Avoid freezing and thawing repeatly.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 4 °C for short term use.Store at -20 °C for long term preservation.

Details zu PTK7

Target: PTK7 (PTK7 Protein tyrosine Kinase 7 (PTK7))

Andere Bezeichnung: PTK7 (PTK7 Produkte)

Synonyme: PTK7 antikoerper, CCK-4 antikoerper, CCK4 antikoerper, Srf antikoerper, 8430404F20Rik antikoerper, chz antikoerper, mPTK7/CCK4 antikoerper, KLG antikoerper, protein tyrosine kinase 7 (inactive) antikoerper, protein tyrosine kinase 7 antikoerper, PTK7 protein tyrosine kinase 7 antikoerper, PTK7 antikoerper, Ptk7 antikoerper

Hintergrund: Protein-tyrosine kinases (PTKs) play important roles in regulating cell proliferation and differentiation during development.One member of the PTK family, PTK7, has been suggested to regulate the planar cell polarity (PCP) pathway in vertebrates and may play a role in neural convergent extension and neural tube closure.PTK7 has also been implicated in the development of cancer.Loss of PTK7 expression was seen in several melanoma cell lines and biopsies.Conversely, high-throughput analysis of acute myeloid leukemia samples showed an increased level of PTK7 expression compared to normal bone marrow and purified CD34+ cells.Multiple isoforms of PTK7 are known to exist.
Synonyms: Protein tyrosine Kinase 7, colon carcinoma kinase-4, CCK-4

Pathways: RTK Signalweg, Tube Formation