CD248 Antikörper (N-Term)

Produktnummer ABIN1887892

Produktdetails anti-CD248 Antikörper

Target: CD248 (CD248 Molecule, Endosialin (CD248))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CD248 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Spezifität: At least two isoforms of TEM1 are known to exist, this antibody recognizes only the larger isoform.

Aufreinigung: Affinity chromatography purified via peptide column

Immunogen: 14 amino acid peptide near the amino terminus of the human TEM1.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Handhabung: Avoid freezing and thawing repeatly.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 4 °C for short term use.Store at -20 °C for long term preservation.

Details zu CD248

Target: CD248 (CD248 Molecule, Endosialin (CD248))

Andere Bezeichnung: TEM1 (CD248 Produkte)

Synonyme: CD164L1 antikoerper, TEM1 antikoerper, 2610111G01Rik antikoerper, AI842296 antikoerper, Cd164l1 antikoerper, Tem1 antikoerper, fb96b12 antikoerper, wu:fb96b12 antikoerper, zgc:162651 antikoerper, CD248 molecule antikoerper, CD248 antigen, endosialin antikoerper, CD248 molecule, endosialin a antikoerper, CD248 antikoerper, Cd248 antikoerper, cd248a antikoerper

Hintergrund: Tumor endothelial marker (TEM) 1 was originally identified as a human embryonic fibroblast-specific antigen and was later determined to be endosialin, a single-pass transmembrane glycoprotein that has multiple extracellular domains, including three EGF-like domains, a sushi-like domain, and a C lectin-like domain.TEM proteins are significantly up-regulated during angiogenesis and neoangiogenesis that are crucial for the growth of solid tumors.While TEM1 is not required for angiogenesis during fetal development, postnatal growth or wound healing, it plays a role in tumor growth, invasion, and metastasis.Fibronectin and collagen types I and IV act as specific ligands of TEM1, leading to suggestions that these molecules may cause changes in the extracellular matrix, cell adhesion and migration during tumor invasion.
Synonyms: Tumor endothelial marker 1, endosialin, CD248, CD164L1

NCBI Accession: NP_065137