CD248 Antikörper (AA 251-350) (Alexa Fluor 647)

Produktnummer ABIN917320

Produktdetails anti-CD248 Antikörper (Alexa Fluor 647)

Target: CD248 (CD248 Molecule, Endosialin (CD248))

Bindungsspezifität: AA 251-350

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CD248 Antikörper ist konjugiert mit Alexa Fluor 647

Applikation: Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Kreuzreaktivität: Human, Maus

Homologie: Rat,Dog,Cow,Pig,Horse

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human TEM 1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: FCM 1:20-100
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Referenzen für anti-CD248 Antikörper (Alexa Fluor 647) (ABIN917320)

Farinon, Clarimundo, Pedrazza, Gulko, Zuanazzi, Xavier, de Oliveira: "Disease modifying anti-rheumatic activity of the alkaloid montanine on experimental arthritis and fibroblast-like synoviocytes." in: European journal of pharmacology, Vol. 799, pp. 180-187, (2017) (PubMed).

Clarimundo, Farinon, Pedó, Teixeira, Nör, Gulko, Xavier, de Oliveira: "Gastrin-releasing peptide and its receptor increase arthritis fibroblast-like synoviocytes invasiveness through activating the PI3K/AKT pathway." in: Peptides, Vol. 95, pp. 57-61, (2017) (PubMed).

Details zu CD248

Target: CD248 (CD248 Molecule, Endosialin (CD248))

Andere Bezeichnung: Tem1/Cd248 (CD248 Produkte)

Synonyme: CD164L1 antikoerper, TEM1 antikoerper, 2610111G01Rik antikoerper, AI842296 antikoerper, Cd164l1 antikoerper, Tem1 antikoerper, fb96b12 antikoerper, wu:fb96b12 antikoerper, zgc:162651 antikoerper, CD248 molecule antikoerper, CD248 antigen, endosialin antikoerper, CD248 molecule, endosialin a antikoerper, CD248 antikoerper, Cd248 antikoerper, cd248a antikoerper

Hintergrund:

Synonyms: TEM1, CD164L1, Endosialin, Tumor endothelial marker 1, CD248

Background: The transmembrane glycoprotein Tumor endothelial marker 1 (TEM1) is highly expressed in tumor endothelial cells however it is barely detectable on normal endothelial cells. It is believed to play a role in tumor angiogenesis. It is expressed in stromal fibroblasts, metastatic hepatic lesions and during angiogenesis of corpus luteum formation and wound healing. TEM1 is being investigated as a potential target for cancer treatment.

Gen-ID: 57124

UniProt: Q9HCU0