CCR8 Antikörper (Extracellular Loop)

Produktnummer ABIN1887798

Produktdetails anti-CCR8 Antikörper

Target: CCR8 (Chemokine (C-C Motif) Receptor 8 (CCR8))

Bindungsspezifität: Extracellular Loop

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CCR8 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Aufreinigung: Affinity chromatography purified via peptide column

Immunogen: Peptide corresponding to amino acids 183 to 201 of human CCR8, which locate in the second extracellular loop.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Handhabung: Avoid freezing and thawing repeatly.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 4 °C for short term use.Store at -20 °C for long term preservation.

Details zu CCR8

Target: CCR8 (Chemokine (C-C Motif) Receptor 8 (CCR8))

Andere Bezeichnung: CCR8 (CCR8 Produkte)

Synonyme: CC-CKR-8 antikoerper, CCR-8 antikoerper, CDw198 antikoerper, CKRL1 antikoerper, CMKBR8 antikoerper, CMKBRL2 antikoerper, CY6 antikoerper, GPRCY6 antikoerper, TER1 antikoerper, C-C antikoerper, C-C CKR-8 antikoerper, CKR-8 antikoerper, Cmkbr8 antikoerper, mCCR8 antikoerper, C-C motif chemokine receptor 8 antikoerper, chemokine (C-C motif) receptor 8 antikoerper, CCR8 antikoerper, Ccr8 antikoerper

Hintergrund: CCR8 is one of the chemokine receptors that are required as coreceptors for HIV infection.The genes encoding human and murine CCR8 were cloned and designated TER1, CKR-L1, and ChemR1.The encoded seven transmembrane protein was identified as the receptor for human CC chemokine I-309 and renamed CCR8.Recently, CCR8 was found to serve as a coreceptor for diverse T-cell tropic, dual-tropic and macrophage-tropic HIV-1 strains.CCR8 mediates CC chemokine I-309 induced monocyte chemoattraction and HIV-1 envelope fusion and virus infection, which can be prevented by the CCR8 ligand I-309.CCR8 is expressed in spleen, thymus and T lymphoblastic cell lines.

Molekulargewicht: 50 kDa