BIM Antikörper (Center)

Produktnummer ABIN1887766

Produktdetails anti-BIM Antikörper

Target: BIM (BCL2L11) (BCL2-Like 11 (Apoptosis Facilitator) (BCL2L11))

Bindungsspezifität: Center

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser BIM Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Aufreinigung: Affinity chromatography purified via peptide column

Immunogen: Peptide corresponding to amino acids near the center of human Bim the sequence is identical to that of mouse and differs from that of rat by one amino acid.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Handhabung: Avoid freezing and thawing repeatly.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 4 °C for short term use.Store at -20 °C for long term preservation.

Details zu BIM

Target: BIM (BCL2L11) (BCL2-Like 11 (Apoptosis Facilitator) (BCL2L11))

Andere Bezeichnung: Bim (BCL2L11 Produkte)

Synonyme: bim antikoerper, BAM antikoerper, BIM antikoerper, BOD antikoerper, 1500006F24Rik antikoerper, Bim antikoerper, Bod antikoerper, BimL antikoerper, BIMEL antikoerper, BCL2-like 11 antikoerper, BCL2 like 11 antikoerper, BCL2-like 11 (apoptosis facilitator) antikoerper, bcl2l11 antikoerper, BCL2L11 antikoerper, Bcl2l11 antikoerper

Hintergrund: Members in the Bcl-2 family are critical regulators of apoptosis by either inhibiting or promoting cell death.Bcl-2 homology 3 (BH3) domain is a potent death domain.BH3 domain containing pro-apoptotic proteins, including Bad, Bax, Bid, Bik, and Hrk, form a growing subclass of the Bcl-2 family.A novel BH3 domain containing protein was recently identified and designated Bim or BOD in human, mouse and rat.Bim/BOD interacts with diverse members in the pro-survival Bcl-2 sub-family including Bcl-2, Bcl-xL and Bcl-w.Bim/BOD induces apoptosis.The messenger RNA of Bim is ubiquitously expressed in multiple tissues and cell lines.
Synonyms: BOD

Molekulargewicht: 23 kDa

UniProt: O43521

Pathways: PI3K-Akt Signalweg, Neurotrophin Signalübertragung, Tube Formation, Positive Regulation of Endopeptidase Activity