WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.
Handhabung
Avoid freezing and thawing repeatly.
Lagerung
4 °C/-20 °C
Informationen zur Lagerung
Store at 4 °C for short term use.Store at -20 °C for long term preservation.
Target
SCARB2
(Scavenger Receptor Class B, Member 2 (SCARB2))
cd36l2 antikoerper, fi13c07 antikoerper, chunp6914 antikoerper, wu:fi13c07 antikoerper, SCARB2 antikoerper, scarb2 antikoerper, AMRF antikoerper, CD36L2 antikoerper, EPM4 antikoerper, HLGP85 antikoerper, LGP85 antikoerper, LIMP-2 antikoerper, LIMPII antikoerper, SR-BII antikoerper, 9330185J12Rik antikoerper, Cd36l2 antikoerper, MLGP85 antikoerper, LimpII antikoerper, scavenger receptor class B, member 2a antikoerper, scavenger receptor class B member 2 antikoerper, scavenger receptor class B, member 2 antikoerper, scarb2a antikoerper, SCARB2 antikoerper, scarb2 antikoerper, Scarb2 antikoerper
Hintergrund
The lysosomal integral membrane protein 2 (LIMP2) is a heavily glycosylated type III transmembrane protein, the majority of which exists in the lumen of the lysosome and a cytoplasmic domain of approximately 20 amino acids.A deficiency of LIMP2 in mice causes uretic pelvic junction obstruction, deafness, and peripheral neuropathy associated with impaired vesicular trafficking and distribution of apically expressed proteins.More recently, LIMP2 was shown to act as a receptor to bind beta-glucocerebrosidase, the enzyme defective in Gaucher disease, a lysosomal storage disorder.LIMP2-deficient mice showed missorted as well as secreted beta-glucocerebrosidase, suggesting that LIMP2 also functions as the mannose-6-phosphate-independent trafficking receptor. Synonyms: Lysosomal integral membrane protein 2, CD36L2, Scavenger receptor class B member 2, SR-B2, SCARB2