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SCARB2 Produkte

(Scavenger Receptor Class B, Member 2 (SCARB2))

Kategorien

The protein encoded by this gene is a type III glycoprotein that is located primarily in limiting membranes of lysosomes and endosomes. Earlier studies in mice and rat suggested that this protein may participate in membrane transportation and the reorganization of endosomal/lysosomal compartment. The protein deficiency in mice was reported to impair cell membrane transport processes and cause pelvic junction obstruction, deafness, and peripheral neuropathy. Further studies in human showed that this protein is a ubiquitously expressed protein and that it is involved in the pathogenesis of HFMD (hand, foot, and mouth disease) caused by enterovirus-71 and possibly by coxsackievirus A16. Mutations in this gene caused an autosomal recessive progressive myoclonic epilepsy-4 (EPM4), also known as action myoclonus-renal failure syndrome (AMRF). Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Feb 2011].

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Ausgewählte SCARB2 Kategorien

SCARB2 Antikörper

High quality antibodies with extensive validation data.

SCARB2 ELISA Kits

Reliable ELISA kits for a wide range of species.

SCARB2 Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene SCARB2 Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Applikation WB, ELISA, IHC, IF
Validierungen
  • (4)
Kat. Nr. ABIN7158800
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Human, Mouse
Applikation WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro)
Validierungen
  • (3)
Kat. Nr. ABIN873185
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, ELISA
Validierungen
  • (3)
Kat. Nr. ABIN560246
Menge 50 μL
Datenblatt Datenblatt

Empfohlene SCARB2 ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN2703297
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Rat
Analytical Method
Validierungen
Kat. Nr. ABIN1141297
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Mouse
Analytical Method
Validierungen
Kat. Nr. ABIN1141296
Menge 96 tests
Datenblatt Datenblatt

Empfohlene SCARB2 Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Mouse
Source Human Cells
Validierungen
  • (1)
Kat. Nr. ABIN7320637
Menge 50 μg
Datenblatt Datenblatt
Reaktivität Mouse
Source Human Cells
Validierungen
  • (1)
Kat. Nr. ABIN7320638
Menge 50 μg
Datenblatt Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1319219
Menge 10 μg
Datenblatt Datenblatt

Neueste Publikationen zu unseren SCARB2 Produkten

Chen, Liu, Zhou, Zhao, Ren, Xiao, Zhu, Qi: "Endophilin-A2-mediated endocytic pathway is critical for enterovirus 71 entry into caco-2 cells." in: Emerging microbes & infections, Vol. 8, Issue 1, pp. 773-786, (2019) (PubMed).

Sun, Tijsma, Mirabelli, Baggen, Wahedi, Franco, De Palma, Leyssen, Verbeken, van Kuppeveld, Neyts, Thibaut: "Intra-host emergence of an enterovirus A71 variant with enhanced PSGL1 usage and neurovirulence." in: Emerging microbes & infections, Vol. 8, Issue 1, pp. 1076-1085, (2019) (PubMed).

Truschel, Clayton, Beckel, Yabes, Yao, Wolf-Johnston, Birder, Apodaca: "Age-related endolysosome dysfunction in the rat urothelium." in: PLoS ONE, Vol. 13, Issue 6, pp. e0198817, (2018) (PubMed).

Wilden, Molina, Feuerborn, Boyle, Lee: "Glutamine-dependent lysosome homeostatic changes induced by starvation and lysosome inhibition." in: Biochimica et biophysica acta. Molecular cell research, Vol. 1865, Issue 9, pp. 1356-1367, (2018) (PubMed).

Gurda, De Guilhem De Lataillade, Bell, Zhu, Yu, Wang, Bagel, Vite, Sikora, Hinderer, Calcedo, Yox, Steet, Ruane, ODonnell, Gao, Wilson, Casal, Ponder, Haskins: "Evaluation of AAV-mediated Gene Therapy for Central Nervous System Disease in Canine Mucopolysaccharidosis VII." in: Molecular therapy : the journal of the American Society of Gene Therapy, Vol. 24, Issue 2, pp. 206-16, (2016) (PubMed).

Marcó, Pujol, Roca, Motas, Ribera, Garcia, Molas, Villacampa, Melia, Sánchez, Sánchez, Bertolin, Ruberte, Haurigot, Bosch: "Progressive neurologic and somatic disease in a novel mouse model of human mucopolysaccharidosis type IIIC." in: Disease models & mechanisms, Vol. 9, Issue 9, pp. 999-1013, (2016) (PubMed).

Liou, Wu, Liao, Chang, Chang, Shih: "A new animal model containing human SCARB2 and lacking stat-1 is highly susceptible to EV71." in: Scientific reports, Vol. 6, pp. 31151, (2016) (PubMed).

Kondo, Maksimova, Otomo, Kato, Imai, Asano, Kobayashi, Nojima, Nakaya, Hamada, Irahara, Gurinova, Sukhomyasova, Nogovicina, Savvina, Yoshimori, Ozono, Sakai: "Mutation in VPS33A affects metabolism of glycosaminoglycans: a new type of mucopolysaccharidosis with severe systemic symptoms." in: Human molecular genetics, Vol. 26, Issue 1, pp. 173-183, (2016) (PubMed).

Lobo, Arenas, Huerta, Sacristán, Pérez-Crespo, Gutiérrez-Adán, Díaz-Gil, Lasunción, Martín-Hidalgo: "Liver growth factor induces testicular regeneration in EDS-treated rats and increases protein levels of class B scavenger receptors." in: American journal of physiology. Endocrinology and metabolism, Vol. 308, Issue 2, pp. E111-21, (2015) (PubMed).

Mareninova, Sendler, Malla, Yakubov, French, Tokhtaeva, Vagin, Oorschot, Lüllmann-Rauch, Blanz, Dawson, Klumperman, Lerch, Mayerle, Gukovsky, Gukovskaya: "Lysosome associated membrane proteins maintain pancreatic acinar cell homeostasis: LAMP-2 deficient mice develop pancreatitis." in: Cellular and molecular gastroenterology and hepatology, Vol. 1, Issue 6, pp. 678-694, (2015) (PubMed).

Synonyme und alternative Namen zu SCARB2

scavenger receptor class B, member 2a (scarb2a), scavenger receptor class B member 2 (SCARB2), scavenger receptor class B member 2 (scarb2), scavenger receptor class B, member 2 (Scarb2), 9330185J12Rik, AMRF, cd36l2, CD36L2, Cd36l2, chunp6914, EPM4, fi13c07, HLGP85, LGP85, LIMP-2, LIMPII, LimpII, MLGP85, SCARB2, scarb2, SR-BII, wu:fi13c07

Bezeichner auf Proteinebene für SCARB2

  • CD36 antigen (collagen type I receptor, thrombospondin receptor)-like 2
  • CD36 antigen-like 2
  • lysosome membrane protein 2
  • scavenger receptor class B, member 2
  • lysosome membrane protein 2-like
  • putative lysosomal integral membrane protein II
  • 85 kDa lysosomal membrane sialoglycoprotein
  • 85 kDa lysosomal sialoglycoprotein scavenger receptor class B, member 2
  • CD36 antigen (collagen type I receptor, thrombospondin receptor)-like 2 (lysosomal integral membrane protein II)
  • LIMP II
  • lysosome membrane protein II
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