SPRED2 Antikörper (Center)

Produktnummer ABIN1887499

Produktdetails anti-SPRED2 Antikörper

Target: SPRED2 (Sprouty-Related, EVH1 Domain Containing 2 (SPRED2))

Bindungsspezifität: Center

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SPRED2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Kreuzreaktivität (Details): This Spred2 antibody is predicted to have no cross-reactivity to Spred1 or Spred3.

Aufreinigung: Affinity chromatography purified via peptide column

Immunogen: 13 amino acid peptide near the center of the human Spred2.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Handhabung: Avoid freezing and thawing repeatly.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 4 °C for short term use.Store at -20 °C for long term preservation.

Details zu SPRED2

Target: SPRED2 (Sprouty-Related, EVH1 Domain Containing 2 (SPRED2))

Andere Bezeichnung: Spred2 (SPRED2 Produkte)

Synonyme: SPRED2 antikoerper, Xspred2 antikoerper, spred-2 antikoerper, Xtspred2 antikoerper, spred2 antikoerper, wu:fb93f08 antikoerper, zgc:77284 antikoerper, Spred-2 antikoerper, C79158 antikoerper, sprouty related EVH1 domain containing 2 antikoerper, sprouty related, EVH1 domain containing 2 antikoerper, sprouty-related, EVH1 domain containing 2b antikoerper, sprouty-related, EVH1 domain containing 2 antikoerper, SPRED2 antikoerper, spred2 antikoerper, spred2b antikoerper, Spred2 antikoerper

Hintergrund: Spred2 is a member of the Sprouty family, a group of proteins that act as negative regulators during development.Like Spred1, Spred2 acts by suppressing the phosphorylation and activation of Raf.The Spred proteins have also been implicated in the negative feedback regulation of FGF signaling in embryogenesis and angiogenesis.Further studies have shown that expression levels of Spred1 and Spred2 proteins are inversely correlated with the incidence of tumor invasion and metastasis in human hepatocellular carcinoma (HHC), suggesting that these proteins could be useful as prognostic factors and therapeutic targets in HCC.At least two isoforms of Spred2 are known to exist.
Synonyms: Sprouty-related EVH1 domain-containing protein 2

NCBI Accession: NP_861449