ECSIT Antikörper (C-Term)

Produktnummer ABIN1887360

Produktdetails anti-ECSIT Antikörper

Target: ECSIT

Bindungsspezifität: C-Term

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ECSIT Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Aufreinigung: Ion exchange chromatography purified

Immunogen: Peptide corresponding to 14 amino acids near the C-terminus of human ECSIT.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Handhabung: Avoid freezing and thawing repeatly.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 4 °C for short term use.Store at -20 °C for long term preservation.

Details zu ECSIT

Target: ECSIT

Andere Bezeichnung: ECSIT (ECSIT Produkte)

Synonyme: CG10610 antikoerper, DmECSIT antikoerper, Dmel\\CG10610 antikoerper, dECSIT antikoerper, ECSIT antikoerper, Sitpec antikoerper, SITPEC antikoerper, CG10610 gene product from transcript CG10610-RA antikoerper, ECSIT signalling integrator antikoerper, ecsit antikoerper, ECSIT signalling integrator S homeolog antikoerper, ECSIT antikoerper, CpipJ_CPIJ003637 antikoerper, Ecsit antikoerper, ecsit.S antikoerper

Hintergrund: Activation of NF-kappaB as a result of Toll-like receptor (TLR) and IL-1 receptor signaling is a major component of innate immune responses.Signals from these receptors are relayed by a number of adapter molecules such as TRIF, TIRAP, and MyD88 to kinases such as IRAK and other intermediates such as TNF receptor associated factor (TRAF)-6.ECSIT (evolutionarily conserved signaling intermediate in Toll pathways) was initially identified as a cytoplasmic protein interacting specifically with TNF receptor associated factor (TRAF)-6 in the TLR pathway.Recently however, ECSIT has also been shown to be required for bone morphogenetic protein (Bmp) signaling and mesoderm formation during mouse embryogenesis, indicating the possibility of cross-talk between the TLR/IL-B and Bmp signaling pathways.

NCBI Accession: NP_057665

Pathways: TLR Signalweg, Toll-Like Receptors Cascades, SARS-CoV-2 Protein Interaktom