TMEM59L Antikörper (C-Term)

Produktnummer ABIN1887271

Produktdetails anti-TMEM59L Antikörper

Target: TMEM59L (Transmembrane Protein 59-Like (TMEM59L))

Bindungsspezifität: C-Term

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TMEM59L Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Kreuzreaktivität (Details): Multiple isoforms of TMEM59L are known to exist. TMEM59L antibody is predicted to not cross-react TMEM59.

Aufreinigung: Affinity chromatography purified via peptide column

Immunogen: 19 amino acid peptide near carboxy terminus of human TMEM59L.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Handhabung: Avoid freezing and thawing repeatly.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 4 °C for short term use.Store at -20 °C for long term preservation.

Details zu TMEM59L

Target: TMEM59L (Transmembrane Protein 59-Like (TMEM59L))

Andere Bezeichnung: TMEM59L (TMEM59L Produkte)

Synonyme: LOC719572 antikoerper, BSMAP antikoerper, C19orf4 antikoerper, 5330410G16Rik antikoerper, RGD1305557 antikoerper, transmembrane protein 59 like antikoerper, transmembrane protein 59-like antikoerper, TMEM59L antikoerper, Tmem59l antikoerper

Hintergrund: Processing of the amyloid precursor protein (APP) by two different proteases, called alpha- and beta-secretase, is a central regulatory event in the generation of the amyloid beta peptide (Abeta), which has a key role in Alzheimer disease (AD) pathogenesis.TMEM59L is a type I membrane glycoprotein that is expressed in the brain.A related protein, TMEM59, is a Golgi-localized protein that modulates the O-glycosylation and complex N-glycosylation steps occurring during the Golgi maturation of several proteins such as APP, BACE1, SEAP or PRNP and inhibits APP transport and shedding.
Synonyms: Transmembrane protein 59L, brain-specific membrane-anchored protein, BSMAP

NCBI Accession: NP_036241