LASS5 Antikörper (C-Term)

Produktnummer ABIN1887230

Produktdetails anti-LASS5 Antikörper

Target: LASS5 (LAG1 Homolog, Ceramide Synthase 5 (LASS5))

Bindungsspezifität: C-Term

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser LASS5 Antikörper ist unkonjugiert

Applikation: ELISA, Western Blotting (WB), Immunofluorescence (IF)

Kreuzreaktivität (Details): Multiple isoforms of LASS5 are known to exist. This antibody may cross-react with the highly homologous LASS6.

Aufreinigung: Affinity chromatography purified via peptide column

Immunogen: 17 amino acid peptide near the carboxy terminus of the human LASS5.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Handhabung: Avoid freezing and thawing repeatly.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 4 °C for short term use.Store at -20 °C for long term preservation.

Details zu LASS5

Target: LASS5 (LAG1 Homolog, Ceramide Synthase 5 (LASS5))

Andere Bezeichnung: LASS5 (LASS5 Produkte)

Synonyme: lass5 antikoerper, trh4 antikoerper, LASS5 antikoerper, Trh4 antikoerper, 2310081H14Rik antikoerper, AU045339 antikoerper, AW544927 antikoerper, Lass5 antikoerper, ceramide synthase 5 antikoerper, ceramide synthase 5 S homeolog antikoerper, CERS5 antikoerper, cers5 antikoerper, cers5.S antikoerper, Cers5 antikoerper

Hintergrund: The LASS (longevity assurance homolog) family members represent a subgroup of the homeobox gene family and are highly conserved from yeasts to mammals.Six members of this family of proteins have been characterized (LASS1-6) and all are involved in ceramide synthesis during cell growth regulation and cancer differentiation.LASS5, also called Trh4, is a 392 amino acid endoplasmic reticulum, multi-pass membrane protein.Functioning as a dihydro-ceramide synthase, LASS5 is involved in the production of sphingolipids containing mainly one fatty acid donor (N-linked palmitoyl-ceramide) in a fumonisin B1-independent manner.It uses palmitoyl-CoA as an acyl donor and is involved in the synthesis of C14, C16 and C18-ceramide.LASS5 is the most abundantly expressed and predominant ceramide synthase isoform in lung epithelia.Recent studies show that LASS5 partially correct growth and apoptosis.
Synonyms: Longevity Assurance Homolog 5, LAG1, TRH4

NCBI Accession: NP_671723