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LASS5 Antikörper (C-Term)

LASS5 Reaktivität: Human, Maus, Ratte WB, IF, EIA Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN500138
  • Target Alle LASS5 Antikörper anzeigen
    LASS5 (LAG1 Homolog, Ceramide Synthase 5 (LASS5))
    Bindungsspezifität
    • 15
    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reaktivität
    • 21
    • 20
    • 6
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Human, Maus, Ratte
    Wirt
    • 34
    • 1
    Kaninchen
    Klonalität
    • 35
    Polyklonal
    Konjugat
    • 11
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser LASS5 Antikörper ist unkonjugiert
    Applikation
    • 24
    • 13
    • 13
    • 11
    • 6
    • 3
    • 3
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)
    Spezifität
    This antibody detects LASS5 C-term). It may cross-react with the highly homologous LASS6.
    Kreuzreaktivität (Details)
    Species reactivity (tested):Human, mouse, rat
    Aufreinigung
    Peptide affinity chromatography
    Immunogen
    LASS5 antibody was raised against a 17 amino acid peptide near the carboxy terminus of the human LASS5.
    Isotyp
    IgG
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  • Applikationshinweise
    ELISA. Western blot: 1 - 2 μg/mL. Immunoflourescence.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Buffer
    PBS containing 0.02 % sodium azide
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freezing and thawing.
    Lagerung
    4 °C/-20 °C
    Informationen zur Lagerung
    Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
  • Target
    LASS5 (LAG1 Homolog, Ceramide Synthase 5 (LASS5))
    Andere Bezeichnung
    LASS5 (LASS5 Produkte)
    Synonyme
    lass5 antikoerper, trh4 antikoerper, LASS5 antikoerper, Trh4 antikoerper, 2310081H14Rik antikoerper, AU045339 antikoerper, AW544927 antikoerper, Lass5 antikoerper, ceramide synthase 5 antikoerper, ceramide synthase 5 S homeolog antikoerper, CERS5 antikoerper, cers5 antikoerper, cers5.S antikoerper, Cers5 antikoerper
    Hintergrund
    The LASS (longevity assurance homolog) family members represent a subgroup of the homeobox gene family and are highly conserved from yeasts to mammals. Six members of this family of proteins have been characterized (LASS1-6) and all are involved in ceramide synthesis during cell growth regulation and cancer differentiation. LASS5, also called Trh4, is a 392 amino acid endoplasmic reticulum, multi-pass membrane protein. Functioning as a dihydro-ceramide synthase, LASS5 is involved in the production of sphingolipids containing mainly one fatty acid donor (N-linked palmitoyl-ceramide) in a fumonisin B1-independent manner. It uses palmitoyl-CoA as an acyl donor and is involved in the synthesis of C14, C16 and C18-ceramide. LASS5 is the most abundantly expressed and predominant ceramide synthase isoform in lung epithelia. Recent studies show that LASS5 partially correct growth and apoptosis. Multiple isoforms of LASS5 are known to exist.Synonyms: LAG1 longevity assurance homolog 5, LASS5, TRAM homolog 4, TRH4, Translocating chain-associating membrane protein homolog 4
    Gen-ID
    91012
    NCBI Accession
    NP_671723
    UniProt
    Q8N5B7
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