ZFYVE26 Antikörper (C-Term)

Produktnummer ABIN1887150

Produktdetails anti-ZFYVE26 Antikörper

Target: ZFYVE26 (Zinc Finger, FYVE Domain Containing 26 (ZFYVE26))

Bindungsspezifität: C-Term

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ZFYVE26 Antikörper ist unkonjugiert

Applikation: ELISA, Western Blotting (WB)

Aufreinigung: Affinity chromatography purified via peptide column

Immunogen: 16 amino acid peptide near the carboxy terminus of human SPG15.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Handhabung: Avoid freezing and thawing repeatly.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 4 °C for short term use.Store at -20 °C for long term preservation.

Details zu ZFYVE26

Target: ZFYVE26 (Zinc Finger, FYVE Domain Containing 26 (ZFYVE26))

Andere Bezeichnung: SPG15 (ZFYVE26 Produkte)

Synonyme: wu:fc33a03 antikoerper, FYVE-CENT antikoerper, SPG15 antikoerper, 4930465A13 antikoerper, 9330197E15Rik antikoerper, A630028O16Rik antikoerper, Gm893 antikoerper, mKIAA0321 antikoerper, zinc finger, FYVE domain containing 26 antikoerper, zinc finger FYVE-type containing 26 antikoerper, zfyve26 antikoerper, ZFYVE26 antikoerper, Zfyve26 antikoerper

Hintergrund: Hereditary spastic paraplegias (HSPs) are genetically and phenotypically heterogeneous disorders.? Spastic paraplegia with thinning of the corpus callosum (ARHSP-TCC) is a relatively frequent form of complicated hereditary spastic paraplegia in which mental retardation and muscle stiffness at onset are followed by slowly progressive paraparesis and cognitive deterioration.SPG15 is the second gene known to be responsible for ARHSP-TCC in the Italian population.Mutations in this gene are associated with autosomal recessive spastic paraplegia-15.SPG15 encodes a protein containing a FYVE zinc finger binding domain which is thought to target these proteins to membrane lipids through interaction with phospholipids in the membrane.SPG15 mRNA is widely distributed in human tissues, as well as in rat embryos, suggesting a possible role for this protein during embryonic development.SPG15 co-localizes partially with endoplasmic reticulum and endosome markers, suggesting a role in intracellular trafficking.Multiple isoforms of SPG15 are known to exist.
Synonyms: Autosomal recessive spastic paraplegia 15, ZFYVE26