CASP14 Antikörper (C-Term)

Produktnummer ABIN1887094

Produktdetails anti-CASP14 Antikörper

Target: CASP14 (Caspase 14, Apoptosis-Related Cysteine Peptidase (CASP14))

Bindungsspezifität: C-Term

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CASP14 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Aufreinigung: Affinity chromatography purified via peptide column

Immunogen: 16 amino acid peptide from near the carboxy terminus of human caspase-14.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Handhabung: Avoid freezing and thawing repeatly.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 4 °C for short term use.Store at -20 °C for long term preservation.

Details zu CASP14

Target: CASP14 (Caspase 14, Apoptosis-Related Cysteine Peptidase (CASP14))

Andere Bezeichnung: Caspase-14 (CASP14 Produkte)

Synonyme: CASP14 antikoerper, MICE antikoerper, mini-ICE antikoerper, caspase 14, apoptosis-related cysteine peptidase antikoerper, caspase 14 antikoerper, caspase-14-like antikoerper, caspase-14 antikoerper, CASP14 antikoerper, Casp14 antikoerper, LOC485601 antikoerper, LOC780455 antikoerper

Hintergrund: Caspases are a family of cysteine proteases that can be divided into apoptotic and inflammatory caspase subfamilies.Unlike the apoptotic caspases, members of the inflammatory subfamily are generally not involved in cell death but are associated with the immune response to microbial pathogens.Members of this subfamily include caspase-1, -4, -5, and -12 and can activate proinflammatory cytokines such as IL-1b and IL-18.Caspase-14 is highly expressed in embryonic but not adult tissues.It is processed and activated by caspase 8 and caspase 10 in vitro, and by anti-Fas agonist antibody or TNF-related apoptosis inducing ligand in vivo.The expression and processing of this caspase may be involved in the keratinocyte terminal differentiation, which is important for the formation of the skin barrier.
Synonyms: Mini-interleukin-1 converting enzyme, Mini-ICE, MICE

NCBI Accession: NP_033939