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CASP14 Antikörper (AA 223-242)

CASP14 Reaktivität: Human, Maus, Ratte WB, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN3030293
  • Target Alle CASP14 Antikörper anzeigen
    CASP14 (Caspase 14, Apoptosis-Related Cysteine Peptidase (CASP14))
    Bindungsspezifität
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 223-242
    Reaktivität
    • 41
    • 18
    • 17
    • 1
    • 1
    Human, Maus, Ratte
    Wirt
    • 39
    • 6
    • 1
    Kaninchen
    Klonalität
    • 30
    • 16
    Polyklonal
    Konjugat
    • 32
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    Dieser CASP14 Antikörper ist unkonjugiert
    Applikation
    • 28
    • 11
    • 8
    • 8
    • 7
    • 6
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Aufreinigung
    Antigen affinity
    Immunogen
    Amino acids 223-242 (KARKTNPEIQSTLRKRLYLQ-human) were used as the immunogen for this Caspase-14 antibody.
    Isotyp
    IgG
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  • Applikationshinweise
    The stated application concentrations are suggested starting points. Titration of the Caspase-14 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL,IHC (Paraffin): 0.5-1 μg/mL
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Buffer
    0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
    Lagerung
    -20 °C
    Informationen zur Lagerung
    After reconstitution, the Caspase-14 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
  • Target
    CASP14 (Caspase 14, Apoptosis-Related Cysteine Peptidase (CASP14))
    Andere Bezeichnung
    Caspase-14 (CASP14 Produkte)
    Synonyme
    CASP14 antikoerper, MICE antikoerper, mini-ICE antikoerper, caspase 14, apoptosis-related cysteine peptidase antikoerper, caspase 14 antikoerper, caspase-14-like antikoerper, caspase-14 antikoerper, CASP14 antikoerper, Casp14 antikoerper, LOC485601 antikoerper, LOC780455 antikoerper
    Hintergrund
    Caspase 14 is an enzyme that in humans is encoded by the CASP14 gene. CASP14 belongs the evolutionarily conserved caspase family. CASP14 was assigned to chromosome 19p13.1. Using Northern blot and semiquantitative RT-PCR analyses, it was showed that CASP14 was transcriptionally upregulated during maintenance of confluent cultures of human epidermal keratinocytes. The expression and processing of this caspase may be involved in keratinocyte terminal differentiation, which is important for the formation of the skin barrier. Caspase 14 seems to play a role in keratinocyte differentiation and cornification and probably regulates maturation of the epidermis by proteolytically processing filaggrin.
    UniProt
    P31944
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