GPR124 Antikörper (C-Term)

Produktnummer ABIN1887082

Produktdetails anti-GPR124 Antikörper

Target: GPR124 (G Protein-Coupled Receptor 124 (GPR124))

Bindungsspezifität: C-Term

Reaktivität: Human, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GPR124 Antikörper ist unkonjugiert

Applikation: ELISA, Immunohistochemistry (IHC), Western Blotting (WB)

Aufreinigung: Affinity chromatography purified via peptide column

Immunogen: 15 amino acid peptide near the carboxy terminus of the human TEM5.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Handhabung: Avoid freezing and thawing repeatly.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 4 °C for short term use.Store at -20 °C for long term preservation.

Details zu GPR124

Target: GPR124 (G Protein-Coupled Receptor 124 (GPR124))

Andere Bezeichnung: TEM5 (GPR124 Produkte)

Synonyme: TEM5 antikoerper, 8430414O08Rik antikoerper, 9530074E10Rik antikoerper, Tem5 antikoerper, mKIAA1531 antikoerper, MGC69043 antikoerper, si:dkey-208c22.2 antikoerper, GPR124 antikoerper, adhesion G protein-coupled receptor A2 antikoerper, adhesion G protein-coupled receptor A2 L homeolog antikoerper, G-protein coupled receptor 124 antikoerper, ADGRA2 antikoerper, Adgra2 antikoerper, adgra2.L antikoerper, adgra2 antikoerper, LOC616111 antikoerper

Hintergrund: Tumor endothelial markers (TEMs) are significantly up-regulated during angiogenesis and neoangiogensis that are crucial for the growth of solid tumors.TEMs localized on the cell surface and conserved across species are of particular interest for future development of anti-angiogenic therapies.These include TEMs such as TEM1, TEM5, TEM7 and TEM8.TEM5 is a member of the adhesion family of G protein coupled receptors and is localized on the surface of endothelial cells.TEM5 is a seven-pass transmembrane receptor, unlike TEM1, TEM7 and TEM8 which span the membrane once.TEM5 is abundantly expressed in tumor vessels, heart, placenta, ovary, small intestine, and colon.Proteolytically processed soluble TEM5 mediates endothelial cell survival during angiogenesis by linking integrin to glycosaminoglycans.
Synonyms: Tumor endothelial marker 5, G protein-coupled receptor 124, GPR124

UniProt: Q96PE1