GPR124 Antikörper (AA 1120-1200)

Produktnummer ABIN7220942

Der Kaninchen Polyklonal anti-GPR124 Antikörper wird verwendet zum Nachweis von GPR124 in Proben von Human und Maus. Er wurde validiert für ELISA, WB und IF.

Kurzübersicht für GPR124 Antikörper (AA 1120-1200) (ABIN7220942)

Target: GPR124 (G Protein-Coupled Receptor 124 (GPR124))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GPR124 Antikörper ist unkonjugiert

Applikation: ELISA, Western Blotting (WB), Immunofluorescence (IF)

Produktdetails anti-GPR124 Antikörper

Bindungsspezifität: AA 1120-1200

Verwendungszweck: Rabbit Anti-GPR124 Polyclonal Antibody

Spezifität: GPR124 Polyclonal Antibody detects endogenous levels of GPR124 protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the C-terminal region of human GPR124 at AA range: 1120-1200

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,IF 1:200-1:1000,ELISA 1:10000,Not yet tested in other applications.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu GPR124

Target: GPR124 (G Protein-Coupled Receptor 124 (GPR124))

Andere Bezeichnung: GPR124

Hintergrund: GPR124, KIAA1531, TEM5, G-protein coupled receptor 124, Tumor endothelial marker 5ADGRA2 (Adhesion G Protein-Coupled Receptor A2) is a Protein Coding gene. Among its related pathways are Integrins in angiogenesis. GO annotations related to this gene include G-protein coupled receptor activity and transmembrane signaling receptor activity. An important paralog of this gene is ADGRA1. ndothelial receptor which functions as a WNT7-specific coactivator of canonical Wnt signaling (By similarity). Required for normal endothelial cell sprouting and migration in the forebrain and neural tube (By similarity). Has a major role in establishing the blood-brain barrier (By similarity). Binds to the glycosaminoglycans heparin, heparin sulfate, chondroitin sulfate and dermatan sulfate (PubMed: 16982628).

Molekulargewicht: 145kD

Gen-ID: 25960

UniProt: Q96PE1