Activin A Receptor Type IB/ALK-4 Antikörper (C-Term)

Produktnummer ABIN1886993

Produktdetails anti-Activin A Receptor Type IB/ALK-4 Antikörper

Target: Activin A Receptor Type IB/ALK-4 (ACVR1B) (Activin A Receptor, Type IB (ACVR1B))

Bindungsspezifität: C-Term

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Activin A Receptor Type IB/ALK-4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Kreuzreaktivität (Details): At least three isoforms of ACVR1B are known to exist. This antibody is predicted to have no cross-reactivity to ACVR1 or ACVR1C.

Aufreinigung: Affinity chromatography purified via peptide column

Immunogen: 14 amino acid peptide near the carboxy terminus of the human ACVR1B.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Handhabung: Avoid freezing and thawing repeatly.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 4 °C for short term use.Store at -20 °C for long term preservation.

Details zu Activin A Receptor Type IB/ALK-4

Target: Activin A Receptor Type IB/ALK-4 (ACVR1B) (Activin A Receptor, Type IB (ACVR1B))

Andere Bezeichnung: ACVR1B (ACVR1B Produkte)

Synonyme: ACVR1B antikoerper, alk4 antikoerper, skr2 antikoerper, alk-4 antikoerper, xalk4 antikoerper, actrib antikoerper, acvrlk4 antikoerper, DKFZp469A1614 antikoerper, 6820432J04 antikoerper, ActR-IB antikoerper, ActRIB antikoerper, Acvrlk4 antikoerper, Alk4 antikoerper, SKR2 antikoerper, ACTRIB antikoerper, ACVRLK4 antikoerper, ALK4 antikoerper, Skr2 antikoerper, axis antikoerper, taram-a antikoerper, tarama antikoerper, wu:fb75f01 antikoerper, activin A receptor type 1B antikoerper, Activin receptor type-1B antikoerper, activin A receptor, type IB antikoerper, activin A receptor, type 1B antikoerper, activin A receptor type 1Ba antikoerper, ACVR1B antikoerper, acvr1b antikoerper, acv1b antikoerper, Acvr1b antikoerper, acvr1ba antikoerper

Hintergrund: Activins are dimeric growth and differentiation factors which belong to the transforming growth factor-beta (TGF-beta) superfamily of structurally related signaling proteins.Activins signal through a heteromeric complex of receptor serine kinases which include at least two type I and two type II receptors.ACVR1B, also known as activin receptor-like kinase 4 (ALK4), is a type I receptor for activin and plays major roles in cell differentiation, growth arrest and apoptosis.Like another type I activin receptor ACVR1C, ACVR1B can mediate signaling by ligands such as Nodal, Xnr1, GDF-1/3, activin B and activin AB.In Xenopus embryos, expression of a dominant-negative form of ACVR1B blocked all mesoderm-inducing ligands, while expression of a dominant negative ACVR1C only blocked Nodal and Xnr1 signaling, suggesting that the ACVR1B and ACVR1C possess distinct functions.
Synonyms: Activin A receptor type IB, Activin receptor-like kinase 4, Activin receptor type 1B precursor, ACTR-IB, ACVRLK4, ALK4, ALK-4

NCBI Accession: NP_001096