NLRP5 Antikörper (C-Term)

Produktnummer ABIN1886982

Produktdetails anti-NLRP5 Antikörper

Target: NLRP5 (NLR Family, Pyrin Domain Containing 5 (NLRP5))

Bindungsspezifität: C-Term

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NLRP5 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Aufreinigung: Affinity chromatography purified via peptide column

Immunogen: 14 amino acid peptide near the carboxy terminus of human NALP5.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Handhabung: Avoid freezing and thawing repeatly.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 4 °C for short term use.Store at -20 °C for long term preservation.

Details zu NLRP5

Target: NLRP5 (NLR Family, Pyrin Domain Containing 5 (NLRP5))

Andere Bezeichnung: NALP5 (NLRP5 Produkte)

Synonyme: CLR19.8 antikoerper, MATER antikoerper, NALP5 antikoerper, PAN11 antikoerper, PYPAF8 antikoerper, Mater antikoerper, Nalp5 antikoerper, Op1 antikoerper, NLR family pyrin domain containing 5 antikoerper, NLR family, pyrin domain containing 5 antikoerper, NLRP5 antikoerper, Nlrp5 antikoerper

Hintergrund: NALP proteins include the apoptosis regulator APAF1 (apoptotic protease activating factor 1) and mammalian NOD-LRR proteins and are thought to be involved in inflammation and reproduction.NALP5, also known as MATER, is a maternal gene required for early embryonic development in mice.Increased NALP5 expression was observed in two neuronal injury models, and transient expression of recombinant NALP5 in neurons induced caspase-3 activation and apoptosis, suggesting that NALP5 also plays a role in caspase activation and apoptosis in injured neurons, and may thus represent a novel target for therapeutic treatment in neurodegenerative disorders.
Synonyms: NLR family pyrin domain containing 5, NLRP5, MATER, PYRIN-containing APAF1-like protein 8, PYPAF8, CLR19.8, PAN11

NCBI Accession: NP_703148

Pathways: Inflammasome