LTBP4 Antikörper (AA 64-256)

Produktnummer ABIN1886594

Produktdetails anti-LTBP4 Antikörper

Target: LTBP4 (Latent Transforming Growth Factor beta Binding Protein 4 (LTBP4))

Bindungsspezifität: AA 64-256

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser LTBP4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF)

Aufreinigung: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein fragment contain a sequence corresponding to a region within amino acids 64 and 256 of LTBP-4

Anwendungsinformationen

Applikationshinweise: Suggested dilutions:
Western blotting: 1.500-1.3000
Immunofluorescence: 1.100-1.200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: 1 x PBS, 1 % BSA, 20 % Glycerol (pH 7.0).0.01 % Thimerosal was added as a preservative.

Konservierungsmittel: Thimerosal (Merthiolate)

Vorsichtsmaßnahmen: Biohazard Informations: This product contains thimerosal which is hazardous.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.

Details zu LTBP4

Target: LTBP4 (Latent Transforming Growth Factor beta Binding Protein 4 (LTBP4))

Andere Bezeichnung: LTBP-4 (LTBP4 Produkte)

Synonyme: ARCL1C antikoerper, LTBP-4 antikoerper, LTBP4L antikoerper, LTBP4S antikoerper, 2310046A13Rik antikoerper, latent transforming growth factor beta binding protein 4 antikoerper, LTBP4 antikoerper, ltbp4 antikoerper, Ltbp4 antikoerper

Hintergrund: Transforming growth factor-beta, or TGFB (see TGFB1, MIM 190180), remains biologically latent after secretion, blocked from activity by its N-terminal propeptide (the latency-associated peptide, or LAP).TGFB is activated by its dissociation from LAP.The latent form of TGFB is secreted in association with a latent TGFB-binding protein, or LTBP (see LTBP1, MIM 150390), and assembled into the extracellular matrix.LTBPs are mainly composed of epidermal growth factor (EGF, MIM 131530)-like repeats and protein domains with 8-cysteine repeats, both of which are also found in fibrillins (e.g., MIM 134797).See Oklu and Hesketh (2000) [PubMed 11104663] for a review of the LTBP gene family.[supplied by OMIM]

Molekulargewicht: 169 kDa

Gen-ID: 8425

NCBI Accession: NM_003573, NP_003564

Pathways: Hormone Transport, Growth Factor Binding