LTBP4 Antikörper (N-Term)

Produktnummer ABIN2855142

Produktdetails anti-LTBP4 Antikörper

Target: LTBP4 (Latent Transforming Growth Factor beta Binding Protein 4 (LTBP4))

Bindungsspezifität: N-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser LTBP4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)

Kreuzreaktivität: Human, Maus

Produktmerkmale: Rabbit Polyclonal antibody to LTBP4 (latent transforming growth factor beta binding protein 4)
LTBP4 antibody [N1N2], N-term

Aufreinigung: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the N-terminus region of human LTBP4. The exact sequence is proprietary.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Kommentare:

Positive Control: Mouse brain , Positive Control: Mouse brain

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1.07 mg/mL

Buffer: 1XPBS pH 7, 20 % Glycerol, 0.025 % ProClin 300

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Details zu LTBP4

Target: LTBP4 (Latent Transforming Growth Factor beta Binding Protein 4 (LTBP4))

Andere Bezeichnung: latent transforming growth factor beta binding protein 4 (LTBP4 Produkte)

Synonyme: ARCL1C antikoerper, LTBP-4 antikoerper, LTBP4L antikoerper, LTBP4S antikoerper, 2310046A13Rik antikoerper, latent transforming growth factor beta binding protein 4 antikoerper, LTBP4 antikoerper, ltbp4 antikoerper, Ltbp4 antikoerper

Hintergrund: Transforming growth factor-beta, or TGFB (see TGFB1, MIM 190180), remains biologically latent after secretion, blocked from activity by its N-terminal propeptide (the latency-associated peptide, or LAP). TGFB is activated by its dissociation from LAP. The latent form of TGFB is secreted in association with a latent TGFB-binding protein, or LTBP (see LTBP1, MIM 150390), and assembled into the extracellular matrix. LTBPs are mainly composed of epidermal growth factor (EGF, MIM 131530)-like repeats and protein domains with 8-cysteine repeats, both of which are also found in fibrillins (e.g., MIM 134797). See Oklu and Hesketh (2000) [PubMed 11104663] for a review of the LTBP gene family.[supplied by OMIM]

Cellular Localization: Secreted , extracellular space , extracellular matrix

Molekulargewicht: 173 kDa

Gen-ID: 8425

UniProt: Q8N2S1

Pathways: Hormone Transport, Growth Factor Binding