ELF3 Antikörper (AA 309-371)

Produktnummer ABIN1886354

Produktdetails anti-ELF3 Antikörper

Target: ELF3 (E74-Like Factor 3 (Ets Domain Transcription Factor, Epithelial-Specific) (ELF3))

Bindungsspezifität: AA 309-371

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ELF3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Aufreinigung: Purified by antigen-affinity chromatography.

Immunogen: Synthetic peptide contain a sequence corresponding to a region within amino acids 309 and 371 of ESE1

Anwendungsinformationen

Applikationshinweise: Suggested dilutions:
Western blotting: 1.500-1.3000
Immunohistochemistry: 1.100-1.250
Immunofluorescence: 1.100-1.200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: 1 x PBS, 1 % BSA, 20 % Glycerol (pH 7.0).0.01 % Thimerosal was added as a preservative.

Konservierungsmittel: Thimerosal (Merthiolate)

Vorsichtsmaßnahmen: Biohazard Informations: This product contains thimerosal which is hazardous.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.

Details zu ELF3

Target: ELF3 (E74-Like Factor 3 (Ets Domain Transcription Factor, Epithelial-Specific) (ELF3))

Andere Bezeichnung: ESE1 (ELF3 Produkte)

Synonyme: ert antikoerper, esx antikoerper, epr-1 antikoerper, ese-1 antikoerper, ESE-1 antikoerper, ESX antikoerper, jen antikoerper, EPR-1 antikoerper, ERT antikoerper, E74 like ETS transcription factor 3 antikoerper, E74-like factor 3 antikoerper, elf3 antikoerper, Elf3 antikoerper, ELF3 antikoerper

Hintergrund: Transcriptional activator that binds and transactivates ETS sequences containing the consensus nucleotide core sequence GGA[AT].Acts synergistically with POU2F3 to transactivate the SPRR2A promoter and with RUNX1 to transactivate the ANGPT1 promoter.Also transactivates collagenase, CCL20, CLND7, FLG, KRT8, NOS2, PTGS2, SPRR2B, TGFBR2 and TGM3 promoters.Represses KRT4 promoter activity.Involved in mediating vascular inflammation.May play an important role in epithelial cell differentiation and tumorigenesis.May be a critical downstream effector of the ERBB2 signaling pathway.May be associated with mammary gland development and involution.Plays an important role in the regulation of transcription with TATA-less promoters in preimplantation embryos, which is essential in preimplantation development.

Molekulargewicht: 41 kDa

Gen-ID: 1999

NCBI Accession: NM_004433, NP_004424