ELF3 Antikörper (AA 147-371)

Produktnummer ABIN7152094

Produktdetails anti-ELF3 Antikörper

Target: ELF3 (E74-Like Factor 3 (Ets Domain Transcription Factor, Epithelial-Specific) (ELF3))

Bindungsspezifität: AA 147-371

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ELF3 Antikörper ist unkonjugiert

Applikation: ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Kreuzreaktivität: Human

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human ETS-related transcription factor Elf-3 protein (147-371AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Recommended dilution: IHC:1:500-1:1000, IF:1:50-1:200,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu ELF3

Target: ELF3 (E74-Like Factor 3 (Ets Domain Transcription Factor, Epithelial-Specific) (ELF3))

Andere Bezeichnung: ELF3 (ELF3 Produkte)

Synonyme: ert antikoerper, esx antikoerper, epr-1 antikoerper, ese-1 antikoerper, ESE-1 antikoerper, ESX antikoerper, jen antikoerper, EPR-1 antikoerper, ERT antikoerper, E74 like ETS transcription factor 3 antikoerper, E74-like factor 3 antikoerper, elf3 antikoerper, Elf3 antikoerper, ELF3 antikoerper

Hintergrund:

Background: Transcriptional activator that binds and transactivates ETS sequences containing the consensus nucleotide core sequence GGA[AT]. Acts synergistically with POU2F3 to transactivate the SPRR2A promoter and with RUNX1 to transactivate the ANGPT1 promoter. Also transactivates collagenase, CCL20, CLND7, FLG, KRT8, NOS2, PTGS2, SPRR2B, TGFBR2 and TGM3 promoters. Represses KRT4 promoter activity. Involved in mediating vascular inflammation. May play an important role in epithelial cell differentiation and tumorigenesis. May be a critical downstream effector of the ERBB2 signaling pathway. May be associated with mammary gland development and involution. Plays an important role in the regulation of transcription with TATA-less promoters in preimplantation embryos, which is essential in preimplantation development (By similarity).

Aliases: E74 like factor 3 antibody, E74 like factor 3 ets domain transcription factor antibody, E74 like factor 3 ets domain transcription factor epithelial specific antibody, E74 like factor 3 ETS domain transcription factor serine box epithelial specific antibody, E74-like factor 3 antibody, Elf3 antibody, ELF3_HUMAN antibody, Epithelial restricted with serine box antibody, Epithelial-restricted with serine box antibody, Epithelium restricted Ets protein ESX antibody, Epithelium specific Ets factor 1 antibody, Epithelium specific Ets transcription factor 1 antibody, Epithelium-restricted Ets protein ESX antibody, Epithelium-specific Ets transcription factor 1 antibody, EPR 1 antibody, EPR1 antibody, ERT antibody, ESE-1 antibody, ESX antibody, Ets domain transcription factor serine box antibody, Ets domain transcription factor serine box epithelial specific antibody, Ets transcription factor antibody, ETS-related transcription factor Elf-3 antibody, jen antibody, MGC139318 antibody

UniProt: P78545