SF3B4 Antikörper (AA 158-187)

Produktnummer ABIN1881796

Produktdetails anti-SF3B4 Antikörper

Target: SF3B4 (Splicing Factor 3b, Subunit 4, 49kDa (SF3B4))

Bindungsspezifität: AA 158-187

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SF3B4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Homologie: M, Rat

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This SF3B4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 158-187 amino acids from the Central region of human SF3B4.

Klon: RB40410

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Haltbarkeit: 6 months

Referenzen für anti-SF3B4 Antikörper (ABIN1881796)

Gudbjartsson, Walters, Thorleifsson, Stefansson, Halldorsson, Zusmanovich, Sulem, Thorlacius, Gylfason, Steinberg, Helgadottir, Ingason, Steinthorsdottir, Olafsdottir, Olafsdottir, Jonsson et al.: "Many sequence variants affecting diversity of adult human height." in: Nature genetics, Vol. 40, Issue 5, pp. 609-15, (2008) (PubMed).

Watanabe, Shionyu, Kimura, Kimata, Watanabe: "Splicing factor 3b subunit 4 binds BMPR-IA and inhibits osteochondral cell differentiation." in: The Journal of biological chemistry, Vol. 282, Issue 28, pp. 20728-38, (2007) (PubMed).

Wu, Ma, Brown, Geisler, Li, Tzeng, Jia, Jurisica, Li: "Systematic identification of SH3 domain-mediated human protein-protein interactions by peptide array target screening." in: Proteomics, Vol. 7, Issue 11, pp. 1775-85, (2007) (PubMed).

Details zu SF3B4

Target: SF3B4 (Splicing Factor 3b, Subunit 4, 49kDa (SF3B4))

Andere Bezeichnung: SF3B4 (SF3B4 Produkte)

Synonyme: chunp6902 antikoerper, fb36a04 antikoerper, wu:fb36a04 antikoerper, 49kDa antikoerper, SF3b49 antikoerper, SF3b50 antikoerper, Sap49 antikoerper, spx antikoerper, AFD1 antikoerper, Hsh49 antikoerper, SAP49 antikoerper, Splicing factor 3B subunit 4 antikoerper, splicing factor 3b, subunit 4 antikoerper, splicing factor 3b subunit 4 S homeolog antikoerper, splicing factor 3b subunit 4 antikoerper, sap-49 antikoerper, sf3b4 antikoerper, Sf3b4 antikoerper, sf3b4.S antikoerper, SF3B4 antikoerper

Hintergrund: This gene encodes one of four subunits of the splicing factor 3B. The protein encoded by this gene cross-links to a region in the pre-mRNA immediately upstream of the branchpoint sequence in pre-mRNA in the prespliceosomal complex A. It also may be involved in the assembly of the B, C and E spliceosomal complexes. In addition to RNA-binding activity, this protein interacts directly and highly specifically with subunit 2 of the splicing factor 3B. This protein contains two N-terminal RNA-recognition motifs (RRMs), consistent with the observation that it binds directly to pre-mRNA.

Molekulargewicht: 44386

NCBI Accession: NP_005841

UniProt: Q15427