SF3B4 Antikörper (N-Term)

Produktnummer ABIN6259186

Produktdetails anti-SF3B4 Antikörper

Target: SF3B4 (Splicing Factor 3b, Subunit 4, 49kDa (SF3B4))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SF3B4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)

Spezifität: SF3B4 Antibody detects endogenous levels of total SF3B4.

Homologie: Pig,Zebrafish,Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus

Aufreinigung: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human SF3B4, corresponding to a region within N-terminal amino acids.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:1000, IHC: 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20 °C. Stable for 12 months from date of receipt.

Haltbarkeit: 12 months

Details zu SF3B4

Target: SF3B4 (Splicing Factor 3b, Subunit 4, 49kDa (SF3B4))

Andere Bezeichnung: SF3B4 (SF3B4 Produkte)

Synonyme: chunp6902 antikoerper, fb36a04 antikoerper, wu:fb36a04 antikoerper, 49kDa antikoerper, SF3b49 antikoerper, SF3b50 antikoerper, Sap49 antikoerper, spx antikoerper, AFD1 antikoerper, Hsh49 antikoerper, SAP49 antikoerper, Splicing factor 3B subunit 4 antikoerper, splicing factor 3b, subunit 4 antikoerper, splicing factor 3b subunit 4 S homeolog antikoerper, splicing factor 3b subunit 4 antikoerper, sap-49 antikoerper, sf3b4 antikoerper, Sf3b4 antikoerper, sf3b4.S antikoerper, SF3B4 antikoerper

Hintergrund:

Description: Involved in pre-mRNA splicing as a component of the splicing factor SF3B complex (PubMed:27720643). SF3B complex is required for 'A' complex assembly formed by the stable binding of U2 snRNP to the branchpoint sequence (BPS) in pre-mRNA. Sequence independent binding of SF3A/SF3B complex upstream of the branch site is essential, it may anchor U2 snRNP to the pre-mRNA (PubMed:12234937). May also be involved in the assembly of the 'E' complex. SF3B4 has been found in complex 'B' and 'C' as well (PubMed:10882114). Belongs also to the minor U12-dependent spliceosome, which is involved in the splicing of rare class of nuclear pre-mRNA intron (PubMed:15146077).

Gene: SF3B4

Molekulargewicht: 55 kDa

Gen-ID: 10262

UniProt: Q15427