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PSMC1 Antikörper (C-Term)

PSMC1 Reaktivität: Human, Maus, Ratte WB, IHC (p), IF Wirt: Kaninchen Polyclonal RB44417 unconjugated
Produktnummer ABIN1881692
  • Target Alle PSMC1 Antikörper anzeigen
    PSMC1 (Proteasome (Prosome, Macropain) 26S Subunit, ATPase, 1 (PSMC1))
    Bindungsspezifität
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 408-436, C-Term
    Reaktivität
    • 22
    • 18
    • 16
    • 5
    • 5
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Human, Maus, Ratte
    Wirt
    • 22
    Kaninchen
    Klonalität
    • 22
    Polyklonal
    Konjugat
    • 15
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser PSMC1 Antikörper ist unkonjugiert
    Applikation
    • 15
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)
    Aufreinigung
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogen
    This PRS4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 408-436 amino acids from the C-terminal region of human PRS4.
    Klon
    RB44417
    Isotyp
    Ig Fraction
  • Applikationshinweise
    IF: 1:25. WB: 1:1000. IHC-P: 1:25
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Haltbarkeit
    6 months
  • Katiyar, Li, Lennarz: "A complex between peptide:N-glycanase and two proteasome-linked proteins suggests a mechanism for the degradation of misfolded glycoproteins." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 101, Issue 38, pp. 13774-9, (2004) (PubMed).

    Matilla, Gorbea, Einum, Townsend, Michalik, van Broeckhoven, Jensen, Murphy, Ptácek, Fu: "Association of ataxin-7 with the proteasome subunit S4 of the 19S regulatory complex." in: Human molecular genetics, Vol. 10, Issue 24, pp. 2821-31, (2001) (PubMed).

    Dubiel, Ferrell, Pratt, Rechsteiner: "Subunit 4 of the 26 S protease is a member of a novel eukaryotic ATPase family." in: The Journal of biological chemistry, Vol. 267, Issue 32, pp. 22699-702, (1992) (PubMed).

  • Target
    PSMC1 (Proteasome (Prosome, Macropain) 26S Subunit, ATPase, 1 (PSMC1))
    Abstract
    PSMC1 Produkte
    Synonyme
    AI325227 antikoerper, P26s4 antikoerper, S4 antikoerper, P26S4 antikoerper, p56 antikoerper, s4 antikoerper, protease (prosome, macropain) 26S subunit, ATPase 1 antikoerper, proteasome 26S subunit, ATPase 1 antikoerper, Psmc1 antikoerper, PSMC1 antikoerper
    Hintergrund
    The 26S protease is involved in the ATP-dependent degradation of ubiquitinated proteins. The regulatory (or ATPase) complex confers ATP dependency and substrate specificity to the 26S complex.
    Molekulargewicht
    49185
    NCBI Accession
    NP_002793
    UniProt
    P62191
    Pathways
    Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA, Ubiquitin Proteasome Pathway
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