NR2E1 Antikörper (AA 75-102)

Produktnummer ABIN1881585

Produktdetails anti-NR2E1 Antikörper

Target: NR2E1 (Nuclear Receptor Subfamily 2, Group E, Member 1 (NR2E1))

Bindungsspezifität: AA 75-102

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NR2E1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Homologie: C, M, X

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This NR2E1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 75-102 amino acids from the Central region of human NR2E1.

Klon: RB41747

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Haltbarkeit: 6 months

Referenzen für anti-NR2E1 Antikörper (ABIN1881585)

Liu, Wang, Belz, Bock, Takacs, Radlwimmer, Barbus, Reifenberger, Lichter, Schütz: "The nuclear receptor tailless induces long-term neural stem cell expansion and brain tumor initiation." in: Genes & development, Vol. 24, Issue 7, pp. 683-95, (2010) (PubMed).

Iwahara, Hisahara, Hayashi, Horio: "Transcriptional activation of NAD+-dependent protein deacetylase SIRT1 by nuclear receptor TLX." in: Biochemical and biophysical research communications, Vol. 386, Issue 4, pp. 671-5, (2009) (PubMed).

de Krom, Staal, Ophoff, Hendriks, Buitelaar, Franke, de Jonge, Bolton, Collier, Curran, van Engeland, van Ree: "A common variant in DRD3 receptor is associated with autism spectrum disorder." in: Biological psychiatry, Vol. 65, Issue 7, pp. 625-30, (2009) (PubMed).

Yokoyama, Takezawa, Schüle, Kitagawa, Kato: "Transrepressive function of TLX requires the histone demethylase LSD1." in: Molecular and cellular biology, Vol. 28, Issue 12, pp. 3995-4003, (2008) (PubMed).

Details zu NR2E1

Target: NR2E1 (Nuclear Receptor Subfamily 2, Group E, Member 1 (NR2E1))

Andere Bezeichnung: NR2E1 (NR2E1 Produkte)

Synonyme: NR2E1 antikoerper, TLL antikoerper, TLX antikoerper, XTLL antikoerper, Mtl1 antikoerper, Mtll antikoerper, Tlx antikoerper, fierce antikoerper, frc antikoerper, tailless antikoerper, fc30e03 antikoerper, fc39f12 antikoerper, wu:fc30e03 antikoerper, wu:fc39f12 antikoerper, zgc:100991 antikoerper, Xtll antikoerper, nr2e1-A antikoerper, tlx antikoerper, nuclear receptor subfamily 2 group E member 1 antikoerper, nuclear receptor subfamily 2, group E, member 1 antikoerper, nuclear receptor subfamily 2 group E member 1 S homeolog antikoerper, NR2E1 antikoerper, Nr2e1 antikoerper, nr2e1 antikoerper, nr2e1.S antikoerper

Hintergrund: Orphan receptor that binds DNA as a monomer to hormone response elements (HRE) containing an extended core motif half-site sequence 5'-AAGGTCA-3' in which the 5' flanking nucleotides participate in determining receptor specificity. May be required for brain development. May be involved in the regulation of retinal development (By similarity).

Molekulargewicht: 42589

NCBI Accession: NP_003260

UniProt: Q9Y466

Pathways: Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway, Stem Cell Maintenance