C-JUN Antikörper (AA 221-250)
Kurzübersicht für C-JUN Antikörper (AA 221-250) (ABIN1881471)
Target
Alle C-JUN (JUN) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Bindungsspezifität
- AA 221-250
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Homologie
- B, C, M, Pig, Rat
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Aufreinigung
- This antibody is purified through a protein A column, followed by peptide affinity purification.
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Immunogen
- This JUN antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 221-250 amino acids from human JUN.
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Isotyp
- Ig Fraction
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Applikationshinweise
- WB: 1:1000. IHC-P: 1:10~50
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C,-20 °C
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Haltbarkeit
- 6 months
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: "Is B-Raf a good therapeutic target for melanoma and other malignancies?" in: Cancer research, Vol. 68, Issue 1, pp. 5-8, (2008) (PubMed).
: "miR-21 Gene expression triggered by AP-1 is sustained through a double-negative feedback mechanism." in: Journal of molecular biology, Vol. 378, Issue 3, pp. 492-504, (2008) (PubMed).
: "Nuclear Dvl, c-Jun, beta-catenin, and TCF form a complex leading to stabilization of beta-catenin-TCF interaction." in: The Journal of cell biology, Vol. 180, Issue 6, pp. 1087-100, (2008) (PubMed).
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: "Is B-Raf a good therapeutic target for melanoma and other malignancies?" in: Cancer research, Vol. 68, Issue 1, pp. 5-8, (2008) (PubMed).
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- C-JUN (JUN) (Jun Proto-Oncogene (JUN))
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Andere Bezeichnung
- JUN
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Hintergrund
- JUN interacts directly with specific target DNA sequences to regulate gene expression.
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Molekulargewicht
- 35676
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NCBI Accession
- NP_002219
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UniProt
- P05412
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Pathways
- MAPK Signalweg, RTK Signalweg, WNT Signalweg, Fc-epsilon Rezeptor Signalübertragung, Activation of Innate immune Response, Myometrial Relaxation and Contraction, Skeletal Muscle Fiber Development, Protein targeting to Nucleus, Toll-Like Receptors Cascades, Autophagie, Signaling of Hepatocyte Growth Factor Receptor, BCR Signaling, S100 Proteine
Target
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