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SMC1A Antikörper
SMC1A
Reaktivität: Human
WB, IHC, ELISA, FACS, IF/ICC
Wirt: Maus
Monoclonal
unconjugated
Produktnummer ABIN1844787
Produktdetails anti-SMC1A Antikörper
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Target
Alle SMC1A Antikörper anzeigen
SMC1A
(Structural Maintenance of Chromosomes 1A (SMC1A))
Reaktivität
Alle Reaktivitäten für SMC1A Antikörper
Human
Wirt
Alle Wirte für SMC1A Antikörper
Maus
Klonalität
Alle Klonalitäten für SMC1A Antikörper
Monoklonal
Konjugat
Alle Konjugate für SMC1A Antikörper
Dieser SMC1A Antikörper ist unkonjugiert
Applikation
Alle Applikationen für SMC1A Antikörper
Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Flow Cytometry (FACS), Immunofluorescence (fixed cells) (IF/ICC)
Aufreinigung
Purified antibody
Immunogen
Purified recombinant fragment of human SMC1 expressed in E. coli.
Isotyp
IgG1
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Alternativen
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Anwendungsinformationen
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Applikationshinweise
Optimal working dilution should be determined by the investigator.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Handhabung
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Format
Liquid
Konzentration
1.0 mg/mL
Buffer
PBS with 0.05 % sodium azide
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
-20 °C
Informationen zur Lagerung
Aliquot and store at -20 °C. Avoid repeated freeze/thaw cycles.
Details zu SMC1A
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Target
SMC1A
(Structural Maintenance of Chromosomes 1A (SMC1A))
Andere Bezeichnung
SMC1 (SMC1A Produkte )
Synonyme
CDLS2 antikoerper, DXS423E antikoerper, SB1.8 antikoerper, SMC1 antikoerper, SMC1L1 antikoerper, SMC1alpha antikoerper, SMCB antikoerper, SMC-1A antikoerper, NV15570 antikoerper, 5830426I24Rik antikoerper, Sb1.8 antikoerper, Smc1 antikoerper, Smc1alpha antikoerper, Smc1l1 antikoerper, Smcb antikoerper, mKIAA0178 antikoerper, smc1 antikoerper, smc1a antikoerper, smc1l1 antikoerper, xSMC1 antikoerper, smc1aa antikoerper, structural maintenance of chromosomes 1A antikoerper, structural maintenance of chromosomes 1A b antikoerper, structural maintenance of chromosomes 1A L homeolog antikoerper, SMC1A antikoerper, smc1a antikoerper, Smc1a antikoerper, smc1ab antikoerper, smc1a.L antikoerper
Hintergrund
Proper cohesion of sister chromatids is a prerequisite for the correct segregation of chromosomes during cell division.The cohesin multiprotein complex is required for sister chromatid cohesion.This complex is composed partly of two structural maintenance of chromosomes (SMC) proteins, SMC3 and either SMC1L2 or the protein encoded by this gene.Most of the cohesin complexes dissociate from the chromosomes before mitosis, although those complexes at the kinetochore remain.Therefore, the encoded protein is thought to be an important part of functional kinetochores.In addition, this protein interacts with BRCA1 and is phosphorylated by ATM, indicating a potential role for this protein in DNA repair.This gene, which belongs to the SMC gene family, is located in an area of the X-chromosome that escapes X inactivation.
Molekulargewicht
143 kDa
Gen-ID
8243
UniProt
Q14683
Pathways
Stem Cell Maintenance
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