MTOR Antikörper (Ser2448)

Produktnummer ABIN1822694

Produktdetails anti-MTOR Antikörper

Target: MTOR (mTOR) (Mechanistic Target of Rapamycin (serine/threonine Kinase) (mTOR))

Bindungsspezifität: Ser2448

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser MTOR Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Immunoprecipitation (IP)

Spezifität: Endogenous levels of human mTOR only when phosphorylated at Ser2448. Species Crossreactivity: mouse, rat.

Aufreinigung: Purified

Immunogen: Synthetic peptide corresponding to residues surrounding Ser2448 of human mTOR.

Type of Immunogen: Synthetic peptide

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Approved: IF (1:50), IP (1:50), WB

Usage: Western Blot: 1:1000 Incubate membrane with diluted antibody in 5 % BSA, 1X TBS, 0.1 % Tween-20 at 4 °C with gentle shaking, overnight.

Kommentare:

Target Species of Antibody: Human

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: 10 mM sodium HEPES,  pH 7.5, 150 mM sodium chloride, 100 μg/mL BSA, less than 0.02 % sodium azide, 50 % glycerol

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Aliquot to avoid repeated freezing and thawing.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: May be stored at 4°C for short-term only. Aliquot to avoid freeze-thaw cycles. Store at -20°C. Aliquots are stable for at least 1 year.

Details zu MTOR

Target: MTOR (mTOR) (Mechanistic Target of Rapamycin (serine/threonine Kinase) (mTOR))

Andere Bezeichnung: MTOR (mTOR Produkte)

Synonyme: FRAP1 antikoerper, FRAP antikoerper, FRAP2 antikoerper, RAFT1 antikoerper, RAPT1 antikoerper, 2610315D21Rik antikoerper, AI327068 antikoerper, Frap1 antikoerper, flat antikoerper, frap1 antikoerper, tor antikoerper, wu:fc22h08 antikoerper, mechanistic target of rapamycin kinase antikoerper, mechanistic target of rapamycin antikoerper, mechanistic target of rapamycin (serine/threonine kinase) antikoerper, MTOR antikoerper, Mtor antikoerper, mtor antikoerper

Hintergrund: Name/Gene ID: MTOR
Subfamily: PI3/PI4
Family: Protein Kinase

Synonyms: MTOR, FRAP1, FRAP2, FRAP, Mammalian target of rapamycin, RAFT1, Rapamycin and FKBP12 target 1, RAPT1, Rapamycin target protein 1

Gen-ID: 2475

UniProt: P42345

Pathways: PI3K-Akt Signalweg, RTK Signalweg, AMPK Signaling, Interferon-gamma Pathway, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Regulation of Actin Filament Polymerization, Regulation of Muscle Cell Differentiation, Regulation of Cell Size, Skeletal Muscle Fiber Development, Regulation of Carbohydrate Metabolic Process, Autophagie, CXCR4-mediated Signaling Events, BCR Signaling, Warburg Effekt