PAI1 Antikörper

Produktnummer ABIN1819351

Produktdetails anti-PAI1 Antikörper

Target: PAI1 (SERPINE1) (Plasminogen Activator Inhibitor 1 (SERPINE1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PAI1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Spezifität: Specifically recognizes human PAI-1 (plasminogen activator inhibitor-1), otherwise known as SERPINE1, a 45kD serine protease inhibitor and member of the serpin family, which acts as the primary inhibitor of tissue plasminogen activator (tPA) and urokinase plasminogen activator (uPA), and hence fibrinolysis. Increased levels of PAI-1 are associated with diabetes, cardiovascular disease and an increased occurrence of thrombosis in obesity, and can be induced by obesity related factors including insulin, glucose and VLDL (very-low-density lipoprotein).

Aufreinigung: Affinity purified

Immunogen: Recombinant Human PAI-1.
ImmunogenType: Recombinant protein

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ELISA (0.5 - 2 μg/mL), IHC-P, WB (0.1 - 0.2 μg/mL),

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Rekonstitution: Distilled water

Konzentration: Lot specific

Buffer: PBS

Handhabung: Aliquot to avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Prior to reconstitution, +4°C. Following reconstitution store at -20°C.

Details zu PAI1

Target: PAI1 (SERPINE1) (Plasminogen Activator Inhibitor 1 (SERPINE1))

Andere Bezeichnung: SERPINE1 / PAI-1 (SERPINE1 Produkte)

Synonyme: PAI antikoerper, PAI-1 antikoerper, PAI1 antikoerper, PLANH1 antikoerper, SERPINE1 antikoerper, si:ch211-138a11.1 antikoerper, Planh1 antikoerper, PAI1A antikoerper, Pai1 antikoerper, Pai1aa antikoerper, Planh antikoerper, RATPAI1A antikoerper, serpin family E member 1 antikoerper, serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 L homeolog antikoerper, serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 antikoerper, serine (or cysteine) peptidase inhibitor, clade E, member 1 antikoerper, SERPINE1 antikoerper, serpine1.L antikoerper, serpine1 antikoerper, Serpine1 antikoerper

Hintergrund: Synonyms :
SERPINE1, PAI1, PLANH1, PAI-1, Serpin E1

Gen-ID: 5054

Pathways: p53 Signalweg, Cellular Response to Molecule of Bacterial Origin, Carbohydrate Homeostasis, Autophagie, Smooth Muscle Cell Migration