MICU1 Antikörper (AA 113-126)

Produktnummer ABIN1804714

Produktdetails anti-MICU1 Antikörper

Target: MICU1 (Mitochondrial Calcium Uptake 1 (MICU1))

Bindungsspezifität: AA 113-126

Reaktivität: Human, Maus, Ratte, Kaninchen, Rind (Kuh), Hund, Pferd, Zebrafisch (Danio rerio), Ziege, Schwein, Huhn, Affe, Xenopus laevis, Hamster, Fledermaus

Wirt: Ziege

Klonalität: Polyklonal

Konjugat: Dieser MICU1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Marke: IHC-plus™

Spezifität: Human CBARA1. This antibody is expected to recognize reported isoforms 1 and 2 (NP_006068.2, NP_001182447.1).

Aufreinigung: Immunoaffinity purified

Immunogen: Synthetic peptide C-EYENRIRAYSTPDK from an internal region of human CBARA1 (NP_006068.2, NP_001182447.1). Percent identity by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Marmoset, Mouse, Rat, Goat, Hamster, Elephant, Panda, Dog, Bat, Bovine, Horse, Rabbit, Pig, Opossum, Turkey, Chicken, Lizard, Xenopus, Stickleback, Pufferfish, Zebrafish, Seq squirt, Ant (100%), Blood fluke, Mosquito, Sea anemone, Water flea, Beetle, Tick (93%), Drosophila (86%).

Type of Immunogen: Synthetic peptide

Anwendungsinformationen

Applikationshinweise: Approved: IHC, IHC-P (3.75 μg/mL), Peptide-ELISA (1:32000), WB (0.5 - 2 μg/mL)

Usage: Peptide ELISA: antibody detection limit dilution 1:32000. Western blot: Approx 55kD band observed in lysates of cell line K562 (calculated MW of 54.6kD according to NP_006068.2). Recommended concentration: 0.5-2 μg/mL. An additional band of unknown identity was also consistently observed at 37kD. This band was successfully blocked by incubation with the immunizing peptide.

Kommentare:

Target Species of Antibody: Human

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Tris-buffered saline,  pH 7.3, 0.5 % BSA, 0.02 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze-thaw cycles.

Referenzen für anti-MICU1 Antikörper (ABIN1804714)

Niemann, Zehm, Waterstradt, Tiedge, Baltrusch: "Cytosolic and mitochondrial Ca2+ concentrations in primary hepatocytes change with ageing and in consequence of an mtDNA mutation." in: Cell calcium, Vol. 82, pp. 102055, (2019) (PubMed).

Details zu MICU1

Target: MICU1 (Mitochondrial Calcium Uptake 1 (MICU1))

Andere Bezeichnung: MICU1 / CBARA1 (MICU1 Produkte)

Synonyme: CALC antikoerper, CBARA1 antikoerper, EFHA3 antikoerper, C730016L05Rik antikoerper, Calc antikoerper, Cbara1 antikoerper, mitochondrial calcium uptake 1 antikoerper, MICU1 antikoerper, Micu1 antikoerper

Hintergrund: Name/Gene ID: MICU1

Synonyms: MICU1, Ara CALC, CBARA1, CALC, EFHA3, Mitochondrial calcium uptake 1, Allergen Hom s 4, Atopy related autoantigen, Atopy-related autoantigen CALC

Gen-ID: 10367

NCBI Accession: NP_006068, NP_001182447

UniProt: Q9BPX6