ARC (AA 2-18) Antikörper

Produktnummer ABIN1731926

Produktdetails

Target: ARC

Bindungsspezifität: AA 2-18

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Unkonjugiert

Applikation: Western Blotting (WB)

Spezifität: Reacts with the human, mouse, and rat ARC.

Aufreinigung: Purified

Immunogen: Peptide corresponding to aa 2-18 of human ARC.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Working dilution: Optimal dilution should be determined by the end user.
The following are guidelines only:
WB(2 μg/mL)

Positive control: HeLa cells

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS, pH 7.4

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Dilute in PBS or medium that is identical to that used in the assay system.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for at least one year at -20°C. Avoid multiple freeze-thaw cycles.

Haltbarkeit: 12 months

Antigendetails

Target: ARC

Synonyme: activity regulated cytoskeleton associated protein antikoerper, Arc antikoerper

Hintergrund: A novel CARD domain-containing protein was recently identified and designated ARC (apoptosis repressor with CARD). ARC interacts with caspase-2 and -8 and inhibits enzymatic activity of caspase-8. ARC suppresses apoptosis induced by cell death adapters FADD and TRADD and by cell death receptors Fas, TNFR-1, and DR3. The mRNA of ARC is primarily expressed in skeletal muscle and cardiac tissue.

Nucleolar protein 3 Apoptosis repressor with CARD Muscle-enriched cytoplasmic protein, Myp Nucleolar protein of 30 kDa, Nop30 Gene name: NOL3, ARC, NOP, FCM,

Gen-ID: 8996

UniProt: O60936