ARC (Middle Region) Antikörper

Produktnummer ABIN2774829

Produktdetails

Target: ARC

Bindungsspezifität: Middle Region

Reaktivität: Human, Maus, Ratte, Meerschweinchen, Rind (Kuh), Ziege

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Sequenz: ELDLPQKQGE PLDQFLWRKR DLYQTLYVDA DEEEIIQYVV GTLQPKLKRF

Homologie: Cow: 100%, Goat: 100%, Guinea Pig: 100%, Human: 100%, Mouse: 100%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against ARC. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human ARC

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 396 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Antigendetails

Target: ARC

Synonyme: activity regulated cytoskeleton associated protein antikoerper, Arc antikoerper

Hintergrund: ARC is required for consolidation of synaptic plasticity as well as formation of long-term memory. It regulates endocytosis of AMPA receptors in response to synaptic activity. The protein is also required for homeostatic synaptic scaling of AMPA receptors.
Alias Symbols: KIAA0278, Arg3.1
Protein Interaction Partner: UBE3A, UBC, KRT15,
Protein Size: 396

Molekulargewicht: 45 kDa

Gen-ID: 23237

NCBI Accession: NM_015193, NP_056008

UniProt: Q7LC44