ARC (AA 191-208) Antikörper

Produktnummer ABIN1731925

Produktdetails

Target: ARC

Bindungsspezifität: AA 191-208

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Spezifität: Reacts with human ARC.

Aufreinigung: Purified

Immunogen: Peptide corresponding to aa 191-208 of human ARC.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Working dilution: Optimal dilution should be determined by the end user.
The following are guidelines only:
IHC (5 μg/mL) WB(1 - 10 μg/mL)

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS, pH 7.4

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Dilute in PBS or medium that is identical to that used in the assay system.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for at least one year at -20°C. Avoid multiple freeze-thaw cycles.

Haltbarkeit: 12 months

Antigendetails

Target: ARC

Synonyme: activity regulated cytoskeleton associated protein antikoerper, Arc antikoerper

Hintergrund: A novel CARD domain-containing protein was recently identified and designated ARC (apoptosis repressor with CARD). ARC interacts with caspase-2 and -8 and inhibits enzymatic activity of caspase-8. ARC suppresses apoptosis induced by cell death adapters FADD and TRADD and by cell death receptors Fas, TNFR-1, and DR3. The messenger RNA of ARC is primarily expressed in skeletal muscle and cardiac tissue.

Nucleolar protein 3 Apoptosis repressor with CARD Muscle-enriched cytoplasmic protein, Myp Nucleolar protein of 30 kDa, Nop30 Gene name: NOL3, NOP

Gen-ID: 8996

UniProt: O60936