AIRE Antikörper (Internal Region)
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- Target Alle AIRE Antikörper anzeigen
- AIRE (Autoimmune Regulator (AIRE))
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Bindungsspezifität
- Internal Region
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Reaktivität
- Human, Ratte, Hund, Rind (Kuh)
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Wirt
- Ziege
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Klonalität
- Polyklonal
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Konjugat
- Dieser AIRE Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Spezifität
- Reacts with human AIRE
- Kreuzreaktivität
- Rind (Kuh), Hund, Ratte (Rattus)
- Kreuzreaktivität (Details)
- This antibody is expected to recognise isoform 1 (NP_000374.1) only. Cross reacts with bovine, canine and rat protein.
- Aufreinigung
- Antigen affinity purified
- Immunogen
- Synthetic peptide C-KDVDLSQPRKGRKP from an internal region of human AIRE (NP_000374.1). Percent identity with other species by BLAST analysis: Human (100%), Gorilla (100%), Rat (100%), Horse (100%), Dog (100%), Hamster (100%), Elephant (100%)
- Top Product
- Discover our top product AIRE Primärantikörper
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- Applikationshinweise
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Working dilution: ELISA (1:32000), IHC-P (2.5 μg/mL), WB (0.5 - 1 μg/mL)
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 0.5 mg/mL
- Buffer
- TBS, pH 7.3, BSA 0.5 % , Sodium azide 0.02 %
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C. Minimize freezing and thawing.
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- Target
- AIRE (Autoimmune Regulator (AIRE))
- Andere Bezeichnung
- AIRE (AIRE Produkte)
- Synonyme
- AIRE1 antikoerper, APECED antikoerper, APS1 antikoerper, APSI antikoerper, PGA1 antikoerper, autoimmune regulator antikoerper, autoimmune regulator (autoimmune polyendocrinopathy candidiasis ectodermal dystrophy) antikoerper, AaeL_AAEL013794 antikoerper, CpipJ_CPIJ001208 antikoerper, CpipJ_CPIJ001209 antikoerper, AIRE antikoerper, Aire antikoerper
- Hintergrund
- Transcriptional regulator that binds to DNA as a dimer or as a tetramer, but not as a monomer. Binds to G-doublets in an A/T-rich environment, the preferred motif is a tandem repeat of 5'-. ATTGGTTA-3' combined with a 5'-TTATTA-3' box. Binds to nucleosomes
- UniProt
- O43918
- Pathways
- Chromatin Binding
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