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CRYAB Antikörper (pSer59) (Cy5.5)

CRYAB Reaktivität: Maus IF (cc), IF (p) Wirt: Kaninchen Polyclonal Cy5.5
Produktnummer ABIN1707000
  • Target Alle CRYAB Antikörper anzeigen
    CRYAB (Crystallin, alpha B (CRYAB))
    Bindungsspezifität
    • 34
    • 29
    • 19
    • 16
    • 15
    • 8
    • 6
    • 6
    • 6
    • 5
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pSer59
    Reaktivität
    • 134
    • 100
    • 87
    • 17
    • 9
    • 8
    • 8
    • 5
    • 4
    • 4
    • 4
    • 3
    • 2
    Maus
    Wirt
    • 160
    • 34
    • 2
    • 1
    Kaninchen
    Klonalität
    • 156
    • 41
    Polyklonal
    Konjugat
    • 81
    • 11
    • 11
    • 9
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    Dieser CRYAB Antikörper ist konjugiert mit Cy5.5
    Applikation
    • 143
    • 79
    • 65
    • 65
    • 63
    • 32
    • 31
    • 29
    • 18
    • 15
    • 8
    • 1
    • 1
    • 1
    Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    Kreuzreaktivität
    Maus
    Homologie
    Human,Rat,Dog,Cow,Sheep,Pig,Horse,Rabbit,Guinea Pig,Hamster
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic phosphopeptide derived from human alpha B Crystallin around the phosphorylation site of Ser59
    Isotyp
    IgG
    Top Product
    Discover our top product CRYAB Primärantikörper
  • Applikationshinweise
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Haltbarkeit
    12 months
  • Target
    CRYAB (Crystallin, alpha B (CRYAB))
    Andere Bezeichnung
    alpha B Crystallin (CRYAB Produkte)
    Synonyme
    CMD1II antikoerper, CRYA2 antikoerper, CTPP2 antikoerper, CTRCT16 antikoerper, HSPB5 antikoerper, MFM2 antikoerper, Crya-2 antikoerper, Crya2 antikoerper, HspB5 antikoerper, AACRYA antikoerper, CRYAB antikoerper, cryab antikoerper, cryab2 antikoerper, wu:fe37f08 antikoerper, zgc:91937 antikoerper, crystallin alpha B antikoerper, crystallin, alpha B antikoerper, hypothetical protein antikoerper, crystallin, alpha B, a antikoerper, crystallin, alpha B, b antikoerper, CRYAB antikoerper, Cryab antikoerper, ZK1128.7 antikoerper, cryaba antikoerper, cryabb antikoerper
    Hintergrund

    Synonyms: alpha B Crystallin phospho S59, alpha B Crystallin phospho Ser59, p-alpha B Crystallin S59, p-alpha B Crystallin Ser59, AACRYA, Alpha B crystallin, Alpha crystallin B chain, Alpha crystallin B chain, AlphaB crystallin, AlphaB-crystallin, Alpha-crystallin B chain, CRYA2, CRYAB, CRYAB_HUMAN, Crystallin alpha B, Crystallin alpha polypeptide 2, CTPP 2, CTPP2, Heat shock 20 kD like protein, Heat shock protein beta 5, Heat shock protein beta-5, HSPB5, NY REN 27 antigen, Renal carcinoma antigen NY REN 27, Renal carcinoma antigen NY-REN-27, Rosenthal fiber component.

    Background: Crystallins are separated into two classes: taxon-specific, or enzyme, and ubiquitous. The latter class constitutes the major proteins of vertebrate eye lens and maintains the transparency and refractive index of the lens. Since lens central fiber cells lose their nuclei during development, these crystallins are made and then retained throughout life, making them extremely stable proteins. Mammalian lens crystallins are divided into alpha, beta, and gamma families, beta and gamma crystallins are also considered as a superfamily. Alpha and beta families are further divided into acidic and basic groups. Seven protein regions exist in crystallins: four homologous motifs, a connecting peptide, and N- and C-terminal extensions. Alpha crystallins are composed of two gene products: alpha-A and alpha-B, for acidic and basic, respectively. Alpha crystallins can be induced by heat shock and are members of the small heat shock protein (sHSP also known as the HSP20) family. They act as molecular chaperones although they do not renature proteins and release them in the fashion of a true chaperone, instead they hold them in large soluble aggregates. Post-translational modifications decrease the ability to chaperone. These heterogeneous aggregates consist of 30-40 subunits, the alpha-A and alpha-B subunits have a 3:1 ratio, respectively. Two additional functions of alpha crystallins are an autokinase activity and participation in the intracellular architecture. Alpha-A and alpha-B gene products are differentially expressed, alpha-A is preferentially restricted to the lens and alpha-B is expressed widely in many tissues and organs. Elevated expression of alpha-B crystallin occurs in many neurological diseases, a missense mutation cosegregated in a family with a desmin-related myopathy. [provided by RefSeq, Jul 2008].

    Gen-ID
    1410
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