PIK3 gamma Antikörper (Cy5)

Details zu Produkt Nr. ABIN1704598
Antigen
Reaktivität
Human, Maus, Ratte (Rattus)
44
44
44
Wirt
Kaninchen
44
Klonalität
Polyklonal
Konjugat
Cy5
3
3
3
3
3
3
3
3
3
3
3
3
3
2
Applikation
Immunofluorescence (Paraffin-embedded Sections) (IF (p))
38
9
9
Optionen
Immunogen KLH conjugated synthetic peptide derived from human PIK3 gamma
Isotyp IgG
Reinigung Purified by Protein A.
Antigen
Hintergrund

This gene encodes a protein that belongs to the pi3/pi4-kinase family of proteins. The gene product is an enzyme that phosphorylates phosphoinositides on the 3-hydroxyl group of the inositol ring. It is an important modulator of extracellular signals, including those elicited by E-cadherin-mediated cell-cell adhesion, which plays an important role in maintenance of the structural and functional integrity of epithelia. In addition to its role in promoting assembly of adherens junctions, the protein is thought to play a pivotal role in the regulation of cytotoxicity in NK cells. The gene is located in a commonly deleted segment of chromosome 7 previously identified in myeloid leukemias. [provided by RefSeq, Jul 2008].

Subcellular location: Cytoplasm

Synonyms: PK3CG_HUMAN, PI 3 Kinase catalytic subunit gamma, Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform, PI3-kinase subunit gamma, PI3K-gamma, PI3Kgamma,

Gen-ID 5294
Applikations-hinweise IF(IHC-P) 1:50-200
Beschränkungen Nur für Forschungszwecke einsetzbar
Format Liquid
Konzentration 1 μg/μL
Buffer Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung 4 °C
Informationen zur Lagerung Store at 4°C
Haltbarkeit 12 months
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