Microtubule-Associated Protein 1 Light Chain 3 alpha (MAP1LC3A) Antikörper (Cy5)

Details zu Produkt Nr. ABIN1704385
Antigen
  • ATG8E
  • LC3
  • LC3A
  • MAP1ALC3
  • MAP1BLC3
  • 1010001H21Rik
  • 4922501H04Rik
  • LC3a
  • MGC69006
  • zgc:77094
  • MGC89867
  • MAP1LC3A
  • map1lc3a
  • microtubule associated protein 1 light chain 3 alpha
  • microtubule-associated protein 1 light chain 3 alpha
  • microtubule associated protein 1 light chain 3 alpha S homeolog
  • MAP1LC3A
  • Map1lc3a
  • map1lc3a.S
  • map1lc3a
Reaktivität
Human, Maus, Ratte (Rattus)
427
230
205
26
15
6
5
4
4
3
3
2
2
2
1
1
1
1
1
Wirt
Kaninchen
379
47
4
2
Klonalität
Polyklonal
Konjugat
Cy5
26
24
23
22
22
18
6
6
6
6
6
5
3
3
3
3
3
3
3
3
3
3
3
3
2
2
1
1
1
1
1
1
1
1
1
1
Applikation
Immunofluorescence (Paraffin-embedded Sections) (IF (p))
347
171
153
94
51
38
34
27
24
21
13
10
6
3
1
Optionen
Immunogen KLH conjugated synthetic peptide derived from human LC3
Isotyp IgG
Reinigung Purified by Protein A.
Antigen
Andere Bezeichnung LC3 (MAP1LC3A Antibody Abstract)
Hintergrund

Ubiquitin-like modifier involved in formation of autophagosomal vacuoles (autophagosomes). Plays a role in mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventing excess ROS production. Whereas LC3s are involved in elongation of the phagophore membrane, the GABARAP/GATE-16 subfamily is essential for a later stage in autophagosome maturation. Promotes primary ciliogenesis by removing OFD1 from centriolar satellites via the autophagic pathway.

Synonyms: LC3A: Microtubule-associated proteins 1A/1B light chain 3A, Autophagy-related protein LC3 A, Autophagy-related ubiquitin-like modifier LC3 A, MAP1 light chain 3-like protein 1, MAP1A/MAP1B light chain 3 A, MAP1A/MAP1B LC3 A, Microtubule-associated protein 1 light chain 3 alpha Microtubule-associated proteins 1A/1B light chain 3B LC3B: Autophagy-related protein LC3 B, Autophagy-related ubiquitin-like modifier LC3 B, MAP1 light chain 3-like protein 2, MAP1A/MAP1B light chain 3 B, MAP1A/MAP1B LC3 B, Microtubule-associated protein 1 light chain 3 beta

Gen-ID 84557, 81631
UniProt Q9H492, Q9GZQ8
Pathways Autophagie
Applikations-hinweise IF(IHC-P) 1:50-200
Beschränkungen Nur für Forschungszwecke einsetzbar
Format Liquid
Konzentration 1 μg/μL
Buffer Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung 4 °C
Informationen zur Lagerung Store at 4°C
Haltbarkeit 12 months
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