CYP11B2 Antikörper (AA 251-350) (Cy5)

Produktnummer ABIN1703879

Produktdetails anti-CYP11B2 Antikörper (Cy5)

Target: CYP11B2 (Cytochrome P450, Family 11, Subfamily B, Polypeptide 2 (CYP11B2))

Bindungsspezifität: AA 251-350

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CYP11B2 Antikörper ist konjugiert mit Cy5

Applikation: Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Kreuzreaktivität: Human

Homologie: Mouse,Rat,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human CYP11B2

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu CYP11B2

Target: CYP11B2 (Cytochrome P450, Family 11, Subfamily B, Polypeptide 2 (CYP11B2))

Andere Bezeichnung: CYP11B2 (CYP11B2 Produkte)

Synonyme: ALDOS antikoerper, CPN2 antikoerper, CYP11B antikoerper, CYP11BL antikoerper, CYPXIB2 antikoerper, P-450C18 antikoerper, P450C18 antikoerper, P450aldo antikoerper, Cpn2 antikoerper, Cyp11b antikoerper, Cyp11b-2 antikoerper, Cp45as antikoerper, Cyp11b3 antikoerper, RNCP45AS antikoerper, cytochrome P450 family 11 subfamily B member 2 antikoerper, cytochrome P450, family 11, subfamily b, polypeptide 2 antikoerper, aldosterone synthase antikoerper, cytochrome P450, family 11, subfamily B, polypeptide 2 antikoerper, cytochrome P450, subfamily XIB (steroid 11-beta-hydroxylase), polypeptide 2 antikoerper, CYP11B2 antikoerper, Cyp11b2 antikoerper

Hintergrund:

Synonyms: CYP 11B2, CYP11B2, CYPXI11B2, Cytochrome P450 1111B2, Cytochrome P450 1111B2 mitochondrial, Cytochrome P450 family 11 subfamily B polypeptide 2, Cytochrome P450 subfamily XIB cholesterol side chain cleavage, Cytochrome P450 subfamily XI11B2, Cytochrome P450C1111B2, C11B2_HUMAN.

Background: This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the mitochondrial inner membrane. The enzyme has steroid 18-hydroxylase activity to synthesize aldosterone and 18-oxocortisol as well as steroid 11 beta-hydroxylase activity. Mutations in this gene cause corticosterone methyl oxidase deficiency. [provided by RefSeq, Jul 2008].

Pathways: ACE Inhibitor Pathway, Metabolism of Steroid Hormones and Vitamin D, Steroid Hormone Biosynthesis, Regulation of Systemic Arterial Blood Pressure by Hormones, C21-Steroid Hormone Metabolic Process, Feeding Behaviour