CYP11B2 Antikörper (Middle Region)

Produktnummer ABIN2776971

Produktdetails anti-CYP11B2 Antikörper

Target: CYP11B2 (Cytochrome P450, Family 11, Subfamily B, Polypeptide 2 (CYP11B2))

Bindungsspezifität: Middle Region

Reaktivität: Human, Pferd

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CYP11B2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: RRLAEAEMLL LLHHVLKHFL VETLTQEDIK MVYSFILRPG TSPLLTFRAI

Homologie: Horse: 79%, Human: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against CYP11B2. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human CYP11B2

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 503 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-CYP11B2 Antikörper (ABIN2776971)

Doi, Satoh, Maekawa, Nakamura, Fustin, Tainaka, Hotta, Takahashi, Morimoto, Takase, Ito, Sasano, Okamura: "Isoform-specific monoclonal antibodies against 3β-hydroxysteroid dehydrogenase/isomerase family provide markers for subclassification of human primary aldosteronism." in: The Journal of clinical endocrinology and metabolism, Vol. 99, Issue 2, pp. E257-62, (2014) (PubMed).

Details zu CYP11B2

Target: CYP11B2 (Cytochrome P450, Family 11, Subfamily B, Polypeptide 2 (CYP11B2))

Andere Bezeichnung: CYP11B2 (CYP11B2 Produkte)

Synonyme: ALDOS antikoerper, CPN2 antikoerper, CYP11B antikoerper, CYP11BL antikoerper, CYPXIB2 antikoerper, P-450C18 antikoerper, P450C18 antikoerper, P450aldo antikoerper, Cpn2 antikoerper, Cyp11b antikoerper, Cyp11b-2 antikoerper, Cp45as antikoerper, Cyp11b3 antikoerper, RNCP45AS antikoerper, cytochrome P450 family 11 subfamily B member 2 antikoerper, cytochrome P450, family 11, subfamily b, polypeptide 2 antikoerper, aldosterone synthase antikoerper, cytochrome P450, family 11, subfamily B, polypeptide 2 antikoerper, cytochrome P450, subfamily XIB (steroid 11-beta-hydroxylase), polypeptide 2 antikoerper, CYP11B2 antikoerper, Cyp11b2 antikoerper

Hintergrund: This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein local
Alias Symbols: ALDOS, CPN2, CYP11B, CYP11BL, P-450C18, P450C18, P450aldo
Protein Interaction Partner: CYP11B2, CYP11B1, CYP11A1, FDX1,
Protein Size: 503

Molekulargewicht: 55 kDa

Gen-ID: 1585

NCBI Accession: NM_000498, NP_000489

UniProt: P19099

Pathways: ACE Inhibitor Pathway, Metabolism of Steroid Hormones and Vitamin D, Steroid Hormone Biosynthesis, Regulation of Systemic Arterial Blood Pressure by Hormones, C21-Steroid Hormone Metabolic Process, Feeding Behaviour