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Prostaglandin D2 Receptor 2 (PTGDR2) (AA 121-220) Antikörper (Biotin)

PTGDR2 Reaktivität: Human WB, ELISA, IHC (p), IHC (fro) Wirt: Kaninchen Polyclonal Biotin
Produktnummer ABIN1700324
  • Target Alle Prostaglandin D2 Receptor 2 (PTGDR2) Antikörper anzeigen
    Prostaglandin D2 Receptor 2 (PTGDR2)
    Bindungsspezifität
    • 14
    • 6
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 121-220
    Reaktivität
    • 65
    • 24
    • 13
    • 4
    • 3
    Human
    Wirt
    • 52
    • 13
    • 1
    Kaninchen
    Klonalität
    • 52
    • 14
    Polyklonal
    Konjugat
    • 28
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Biotin
    Applikation
    • 27
    • 17
    • 13
    • 13
    • 13
    • 12
    • 7
    • 7
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    Kreuzreaktivität
    Human
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human GPR44/CD294
    Isotyp
    IgG
    Top Product
    Discover our top product PTGDR2 Primärantikörper
  • Applikationshinweise
    WB 1:300-5000
    IHC-P 1:200-400
    IHC-F 1:100-500
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C for 12 months.
    Haltbarkeit
    12 months
  • Target
    Prostaglandin D2 Receptor 2 (PTGDR2)
    Andere Bezeichnung
    GPR44 (PTGDR2 Produkte)
    Synonyme
    CD294 antikoerper, CRTH2 antikoerper, DL1R antikoerper, DP2 antikoerper, GPR44 antikoerper, Crth2 antikoerper, Grp45 antikoerper, Ptgdr2 antikoerper, Gpr44 antikoerper, prostaglandin D2 receptor 2 antikoerper, PTGDR2 antikoerper, Ptgdr2 antikoerper
    Hintergrund

    Synonyms: DP2, DL1R, CD294, CRTH2, GPR44, Prostaglandin D2 receptor 2, Chemoattractant receptor-homologous molecule expressed on Th2 cells, G-protein coupled receptor 44, PTGDR2

    Background: Receptor for prostaglandin D2 (PGD2). Coupled to the G(i)-protein. Receptor activation may result in pertussis toxin-sensitive decreases in cAMP levels and Ca(2+) mobilization. PI3K signaling is also implicated in mediating PTGDR2 effects. PGD2 induced receptor internalization. CRTH2 internalization can be regulated by diverse kinases such as, PKC, PKA, ADRBK1/GRK2, GPRK5/GRK5 and GRK6. Receptor activation is responsible, at least in part, in immune regulation and allergic/inflammation responses.

    Gen-ID
    11251
    UniProt
    Q9Y5Y4
    Pathways
    Regulation of G-Protein Coupled Receptor Protein Signaling
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