Prostaglandin D2 Receptor 2 (PTGDR2) (AA 121-220) Antikörper (Biotin)
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- Target Alle Prostaglandin D2 Receptor 2 (PTGDR2) Antikörper anzeigen
- Prostaglandin D2 Receptor 2 (PTGDR2)
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Bindungsspezifität
- AA 121-220
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Biotin
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Applikation
- Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
- Kreuzreaktivität
- Human
- Aufreinigung
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human GPR44/CD294
- Isotyp
- IgG
- Top Product
- Discover our top product PTGDR2 Primärantikörper
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- Applikationshinweise
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WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500 - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Konservierungsmittel
- ProClin
- Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C for 12 months.
- Haltbarkeit
- 12 months
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- Target
- Prostaglandin D2 Receptor 2 (PTGDR2)
- Andere Bezeichnung
- GPR44 (PTGDR2 Produkte)
- Synonyme
- CD294 antikoerper, CRTH2 antikoerper, DL1R antikoerper, DP2 antikoerper, GPR44 antikoerper, Crth2 antikoerper, Grp45 antikoerper, Ptgdr2 antikoerper, Gpr44 antikoerper, prostaglandin D2 receptor 2 antikoerper, PTGDR2 antikoerper, Ptgdr2 antikoerper
- Hintergrund
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Synonyms: DP2, DL1R, CD294, CRTH2, GPR44, Prostaglandin D2 receptor 2, Chemoattractant receptor-homologous molecule expressed on Th2 cells, G-protein coupled receptor 44, PTGDR2
Background: Receptor for prostaglandin D2 (PGD2). Coupled to the G(i)-protein. Receptor activation may result in pertussis toxin-sensitive decreases in cAMP levels and Ca(2+) mobilization. PI3K signaling is also implicated in mediating PTGDR2 effects. PGD2 induced receptor internalization. CRTH2 internalization can be regulated by diverse kinases such as, PKC, PKA, ADRBK1/GRK2, GPRK5/GRK5 and GRK6. Receptor activation is responsible, at least in part, in immune regulation and allergic/inflammation responses.
- Gen-ID
- 11251
- UniProt
- Q9Y5Y4
- Pathways
- Regulation of G-Protein Coupled Receptor Protein Signaling
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