ASPSCR1 Antikörper (AA 351-420) (Alexa Fluor 647)

Produktnummer ABIN1698608

Produktdetails anti-ASPSCR1 Antikörper (Alexa Fluor 647)

Target: ASPSCR1 (Alveolar Soft Part Sarcoma Chromosome Region, Candidate 1 (ASPSCR1))

Bindungsspezifität: AA 351-420

Reaktivität: Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ASPSCR1 Antikörper ist konjugiert mit Alexa Fluor 647

Applikation: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Kreuzreaktivität: Maus, Ratte

Homologie: Human

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human TUG/ASPC

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu ASPSCR1

Target: ASPSCR1 (Alveolar Soft Part Sarcoma Chromosome Region, Candidate 1 (ASPSCR1))

Andere Bezeichnung: TUG/ASPC (ASPSCR1 Produkte)

Synonyme: tug antikoerper, aspl antikoerper, asps antikoerper, rcc17 antikoerper, ubxd9 antikoerper, aspcr1 antikoerper, ASPCR1 antikoerper, ASPL antikoerper, ASPS antikoerper, RCC17 antikoerper, TUG antikoerper, UBXD9 antikoerper, UBXN9 antikoerper, 1190006K01Rik antikoerper, ASPC antikoerper, ASPSCR1, UBX domain containing tether for SLC2A4 antikoerper, alveolar soft part sarcoma chromosome region, candidate 1 S homeolog antikoerper, alveolar soft part sarcoma chromosome region, candidate 1 antikoerper, alveolar soft part sarcoma chromosome region, candidate 1 (human) antikoerper, ASPSCR1 antikoerper, aspscr1.S antikoerper, Aspscr1 antikoerper, aspscr1 antikoerper, Bm1_55980 antikoerper

Hintergrund:

Synonyms: Alveolar soft part sarcoma chromosomal region candidate gene 1 protein, Alveolar soft part sarcoma chromosome region candidate 1 human, Alveolar soft part sarcoma locus, ASPC, ASPC1_HUMAN, ASPCR 1, ASPCR1, ASPL, ASPS, ASPSCR 1, Aspscr1, FLJ45380, RCC 17, RCC17, renal cell carcinoma gene on chromosome 17, renal cell carcinoma papillary 17, Renal papillary cell carcinoma protein 17, Tether containing a UBX domain for GLUT4, Tether containing UBX domain for GLUT4, TUG, UBX domain containing protein 9, UBX domain protein 9, UBX domain-containing protein 9, UBXD 9, UBXD9, UBXN 9, UBXN9.

Background: Glut4 is a twelve pass transmembrane protein (12TM) whose carboxy-terminus may dictate its cellular localization. Aberrant Glut4 expression has been suggested to contribute to such maladies as obesity and diabetes. Glut4 null mice have shown that while functional Glut4 protein is not required for maintaining normal glucose levels, it is necessary for sustained growth, normal cellular glucose, fat metabolism and prolonged longevity. TUG (ASPL in humans) regulates the trafficking of glucose via Glut4. Full-length TUG forms a complex with Glut4 and in 3T3-L1 adipocytes and this complex is present in unstimulated cells and is disassembled by insulin. TUG acts by trapping endocytosed Glut4 and tethering it intracellularly. Insulin mobilizes this pool of retained Glut4 by releasing the tether.

Gen-ID: 79058