ASPSCR1 Antikörper

Produktnummer ABIN1724649

Produktdetails anti-ASPSCR1 Antikörper

Target: ASPSCR1 (Alveolar Soft Part Sarcoma Chromosome Region, Candidate 1 (ASPSCR1))

Reaktivität: Maus

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser ASPSCR1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Aufreinigung: Purified

Immunogen: Purified recombinant fragment of TUG expressed in E. Coli.

Klon: 4A11A6G11

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: ELISA: 1:10000, WB: 1:500 - 1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS containing 0.03 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: 4°C, -20°C for long term storage

Referenzen für anti-ASPSCR1 Antikörper (ABIN1724649)

Bogan, Hendon, McKee, Tsao, Lodish: "Functional cloning of TUG as a regulator of GLUT4 glucose transporter trafficking." in: Nature, Vol. 425, Issue 6959, pp. 727-33, (2003) (PubMed).

Details zu ASPSCR1

Target: ASPSCR1 (Alveolar Soft Part Sarcoma Chromosome Region, Candidate 1 (ASPSCR1))

Andere Bezeichnung: TUG (ASPSCR1 Produkte)

Synonyme: tug antikoerper, aspl antikoerper, asps antikoerper, rcc17 antikoerper, ubxd9 antikoerper, aspcr1 antikoerper, ASPCR1 antikoerper, ASPL antikoerper, ASPS antikoerper, RCC17 antikoerper, TUG antikoerper, UBXD9 antikoerper, UBXN9 antikoerper, 1190006K01Rik antikoerper, ASPC antikoerper, ASPSCR1, UBX domain containing tether for SLC2A4 antikoerper, alveolar soft part sarcoma chromosome region, candidate 1 S homeolog antikoerper, alveolar soft part sarcoma chromosome region, candidate 1 antikoerper, alveolar soft part sarcoma chromosome region, candidate 1 (human) antikoerper, ASPSCR1 antikoerper, aspscr1.S antikoerper, Aspscr1 antikoerper, aspscr1 antikoerper, Bm1_55980 antikoerper

Hintergrund: The TUG protein contains a UBX domain, for GLUT4. In truncated form, TUG acts in a dominant-negative manner to inhibit insulin-stimulated GLUT4 redistribution in Chinese hamster ovary cells and 3T3-L1 adipocytes. Full-length TUG forms a complex specifically with GLUT4. In 3T3-L1 adipocytes, this complex is present in unstimulated cells and is largely disassembled by insulin. Endogenous TUG is localized with the insulin-mobilizable pool of GLUT4 in unstimulated 3T3-L1 adipocytes, and is not mobilized to the plasma membrane by insulin.

Gen-ID: 79058

HGNC: 79058