ASPSCR1 Antikörper

Produktnummer ABIN7265566

Dieser Kaninchen Monoklonal Antikörper detektiert spezifisch ASPSCR1 in WB. Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für ASPSCR1 Antikörper (ABIN7265566)

Target: ASPSCR1 (Alveolar Soft Part Sarcoma Chromosome Region, Candidate 1 (ASPSCR1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser ASPSCR1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-ASPSCR1 Antikörper

Verwendungszweck: TUG/ASPSCR1 Rabbit mAb

Kreuzreaktivität: Human, Maus

Produktmerkmale: Monoclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: A synthesized peptide derived from human TUG/ASPSCR1.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu ASPSCR1

Target: ASPSCR1 (Alveolar Soft Part Sarcoma Chromosome Region, Candidate 1 (ASPSCR1))

Andere Bezeichnung: TUG

Hintergrund: The protein encoded by this gene contains a UBX domain and interacts with glucose transporter type 4 (GLUT4). This protein is a tether, which sequesters the GLUT4 in intracellular vesicles in muscle and fat cells in the absence of insulin, and redistributes the GLUT4 to the plasma membrane within minutes of insulin stimulation. Translocation t(X,17)(p11,q25) of this gene with transcription factor TFE3 gene results in a ASPSCR1-TFE3 fusion protein in alveolar soft part sarcoma and in renal cell carcinomas. Multiple alternatively spliced transcript variants have been found.,ASPSCR1, ASPCR1, ASPL, ASPS, RCC17, TUG, UBXD9, UBXN9, tether containing UBX domain for GLUT4,Cancer,Signal Transduction,Cell Biology & Developmental Biology,Growth factor,Endocrine & Metabolism,Lipid Metabolism,TUG

Molekulargewicht: 70-80kDa

Gen-ID: 79058

UniProt: Q9BZE9