PAG1 Antikörper (AA 331-432) (Alexa Fluor 555)
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- Target Alle PAG1 Antikörper anzeigen
- PAG1 (phosphoprotein Associated with Glycosphingolipid Microdomains 1 (PAG1))
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Bindungsspezifität
- AA 331-432
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Reaktivität
- Maus, Ratte
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser PAG1 Antikörper ist konjugiert mit Alexa Fluor 555
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Applikation
- Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- Kreuzreaktivität
- Maus, Ratte
- Homologie
- Human,Dog,Horse,Rabbit
- Aufreinigung
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human PAG1
- Isotyp
- IgG
- Top Product
- Discover our top product PAG1 Primärantikörper
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- Applikationshinweise
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FCM 1:20-100
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Konservierungsmittel
- ProClin
- Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Haltbarkeit
- 12 months
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- Target
- PAG1 (phosphoprotein Associated with Glycosphingolipid Microdomains 1 (PAG1))
- Andere Bezeichnung
- Pag1 (PAG1 Produkte)
- Synonyme
- Cbp antikoerper, F730007C19Rik antikoerper, Pag antikoerper, CBP antikoerper, PAG antikoerper, MGC80192 antikoerper, phosphoprotein associated with glycosphingolipid microdomains 1 antikoerper, phosphoprotein membrane anchor with glycosphingolipid microdomains 1 antikoerper, phosphoprotein membrane anchor with glycosphingolipid microdomains 1 L homeolog antikoerper, Pag1 antikoerper, PAG1 antikoerper, pag1.L antikoerper, pag1 antikoerper
- Hintergrund
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Synonyms: CBP, PAG, Phosphoprotein associated with glycosphingolipid-enriched microdomains 1, Csk-binding protein, Transmembrane adapter protein PAG, Transmembrane phosphoprotein Cbp, PAG1
Background: Negatively regulates TCR (T-cell antigen receptor)-mediated signaling in T-cells and FCER1 (high affinity immunoglobulin epsilon receptor)-mediated signaling in mast cells. Promotes CSK activation and recruitment to lipid rafts, which results in LCK inhibition. Inhibits immunological synapse formation by preventing dynamic arrangement of lipid raft proteins. May be involved in cell adhesion signaling.
- Gen-ID
- 55824
- UniProt
- Q9NWQ8
- Pathways
- p53 Signalweg, T-Zell Rezeptor Signalweg, EGFR Signaling Pathway, CXCR4-mediated Signaling Events
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