ARNTL Antikörper

Produktnummer ABIN7101726

Produktdetails anti-ARNTL Antikörper

Target: ARNTL (Aryl Hydrocarbon Receptor Nuclear Translocator-Like (ARNTL))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser ARNTL Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Kreuzreaktivität: Ratte

Produktmerkmale: Monoclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: A synthesized peptide derived from human BMAL1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu ARNTL

Target: ARNTL (Aryl Hydrocarbon Receptor Nuclear Translocator-Like (ARNTL))

Andere Bezeichnung: ARNTL (ARNTL Produkte)

Synonyme: BMAL1 antikoerper, BMAL1c antikoerper, JAP3 antikoerper, MOP3 antikoerper, PASD3 antikoerper, TIC antikoerper, bHLHe5 antikoerper, Bmal1 antikoerper, ARNTL antikoerper, xBmal1 antikoerper, arntl antikoerper, Arnt3 antikoerper, BMAL1b antikoerper, bmal1b' antikoerper, aryl hydrocarbon receptor nuclear translocator like antikoerper, aryl hydrocarbon receptor nuclear translocator-like antikoerper, aryl hydrocarbon receptor nuclear translocator like S homeolog antikoerper, ARNTL antikoerper, Arntl antikoerper, arntl.S antikoerper, arntl antikoerper

Hintergrund: The protein encoded by this gene is a basic helix-loop-helix protein that forms a heterodimer with CLOCK. This heterodimer binds E-box enhancer elements upstream of Period (PER1, PER2, PER3) and Cryptochrome (CRY1, CRY2) genes and activates transcription of these genes. PER and CRY proteins heterodimerize and repress their own transcription by interacting in a feedback loop with CLOCK/ARNTL complexes. Defects in this gene have been linked to infertility, problems with gluconeogenesis and lipogenesis, and altered sleep patterns. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2014],BMAL1, BMAL1c, JAP3, MOP3, PASD3, TIC, bHLHe5,Blood,Blood_Blood Pressure regulation,Cancer,Cardiovascular,Endocrine & Metabolism,Epigenetics & Nuclear Signaling,Heart,Heart_Cardiac metabolism,Lipid Metabolism,Lipid Metabolism_Cholesterol Metabolism,Lipids,Neuroscience,Transcription Factors,ARNTL

Molekulargewicht: 68 kDa

Gen-ID: 406

UniProt: O00327

Pathways: Regulation of Lipid Metabolism by PPARalpha, Protein targeting to Nucleus, Warburg Effekt