NMDAR2A Antikörper (AA 1130-1400)

Produktnummer ABIN1681064

Produktdetails anti-NMDAR2A Antikörper

Target: NMDAR2A (GRIN2A) (Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 2a (GRIN2A))

Bindungsspezifität: AA 1130-1400

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NMDAR2A Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF)

Sequenz: LDPPQFVENV TLPENVDFPD PYQDPSENFR KGDSTLPMNR NPLHNEEGLS NNDQYKLYSK HFTLKDKGSP HSETSERYRQ NSTHCRSCLS NMPTYSGHFT MRSPFKCDAC LRMGNLYDID EDQMLQETGN PATGEQVYQQ DWAQNNALQL QKNKLRISRQ HSYDNIVDKP RELDLSRPSR SISLKDRERL LEGNFYGSLF SVPSSKLSGK KSSLFPQGLE DSKRSKSLLP DHTSDNPFLH SHRDDQRLVI GRCPSDPYKH SLPSQAVNDS Y

Kreuzreaktivität: Maus, Ratte

Produktmerkmale: Polyclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1130-1400 of human NMDAR2A (NP_000824.1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:1000,IF,1:50 - 1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu NMDAR2A

Target: NMDAR2A (GRIN2A) (Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 2a (GRIN2A))

Andere Bezeichnung: GRIN2A (GRIN2A Produkte)

Synonyme: NMDAR2A antikoerper, nr2a antikoerper, GRIN2A antikoerper, EPND antikoerper, GluN2A antikoerper, NR2A antikoerper, glutamate ionotropic receptor NMDA type subunit 2A antikoerper, glutamate receptor, ionotropic, N-methyl D-aspartate 2A L homeolog antikoerper, glutamate receptor ionotropic, NMDA 2A antikoerper, glutamate receptor, ionotropic, NMDA2A (epsilon 1) antikoerper, GRIN2A antikoerper, grin2a.L antikoerper, LOC100438553 antikoerper, Grin2a antikoerper

Hintergrund: This gene encodes a member of the glutamate-gated ion channel protein family. The encoded protein is an N-methyl-D-aspartate (NMDA) receptor subunit. NMDA receptors are both ligand-gated and voltage-dependent, and are involved in long-term potentiation, an activity-dependent increase in the efficiency of synaptic transmission thought to underlie certain kinds of memory and learning. These receptors are permeable to calcium ions, and activation results in a calcium influx into post-synaptic cells, which results in the activation of several signaling cascades. Disruption of this gene is associated with focal epilepsy and speech disorder with or without mental retardation. Alternative splicing results in multiple transcript variants.,EPND,FESD,GluN2A,LKS,NMDAR2A,NR2A,GRIN2A,NMDA 2A,Neuroscience,Neurodegenerative Diseases,Amyloid Plaque and Neurofibrillary Tangle Formation in Alzheimer's Disease,Dopamine Signaling in Parkinson's Disease,Neurodegenerative Diseases Markers,Other Neurological disorders,Cerebralvascular accident-CVA,GRIN2A

Molekulargewicht: 144 kDa/165 kDa

Gen-ID: 2903

UniProt: Q12879

Pathways: Synaptic Membrane, Regulation of long-term Neuronal Synaptic Plasticity